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60569-15-5

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60569-15-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 60569-15-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,6 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60569-15:
(7*6)+(6*0)+(5*5)+(4*6)+(3*9)+(2*1)+(1*5)=125
125 % 10 = 5
So 60569-15-5 is a valid CAS Registry Number.

60569-15-5Relevant articles and documents

Synthesis and bioevaluation of 2-phenyl-5-methyl-2H-1,2,3-triazole-4-carboxylic acid/carbohydrazide derivatives as potent xanthine oxidase inhibitors

Shi, Ailong,Wang, Defa,Wang, He,Wu, Yue,Tian, Haiqiu,Guan, Qi,Bao, Kai,Zhang, Weige

, p. 114879 - 114888 (2016/12/24)

A series of 2-phenyl-5-methyl-2H-1,2,3-triazole-4-carboxylic acids/carbohydrazides as analogues of febuxostat were synthesized and evaluated for their in vitro xanthine oxidase (XO) inhibitory activity. Among these compounds, the carboxylic acid derivatives 7a-h and 8a-h exhibited high potency in the submicromolar/nanomolar range. Steady-state kinetics experiment revealed that 7f was a mixed-type inhibitor of xanthine oxidase. In addition, a molecular docking study of 7f was performed to determine its binding mode at the active site of xanthine oxidase.

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