60569-19-9

Usage

Uses

Used in Pharmaceutical Industry:
(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate is used as an intermediate in the synthesis of pharmaceutical compounds for its potential pharmacological properties. Its precise chemical structure enables specific interactions with target molecules in biological systems, contributing to the development of new drugs.
Used in Research and Development:
(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate is utilized in research and development for the exploration of its potential applications in the pharmaceutical field. Its unique chemical structure and properties make it a valuable compound for studying and understanding the interactions with biological systems.
Safety Precautions:
(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate should be handled and used with caution, as it may pose health hazards. It is essential to store and dispose of this chemical compound properly according to safety regulations to minimize any potential risks associated with its use.

InChI:InChI=1/C24H31NO2/c1-3-4-17-24(20-11-7-5-8-12-20,21-13-9-6-10-14-21)23(26)27-22-15-18-25(2)19-16-22/h5-14,22H,3-4,15-19H2,1-2H3

Upstream product

• 54556-98-8 propiverine hydrochloride 
• 106-52-5 N-methyl-4-hydroxypiperidine 
• 93903-17-4 methyl 2,2-diphenyl-2-propyloxy-acetate 

Downstream Products

• 3608-67-1 N-methyl-4-piperidyl benzilate 
• 118108-71-7 Diphenyl(1-propoxy)essigsaeure(1'-methylpiperid-4'-yl)ester-N-oxide 
• 118108-72-8 Diphenyl(1-propoxy)essigsaeure(1'-methylpiperid-4'-yl)ester-N-oxide 
• 1558012-71-7 1,1-dimethyl-4-[(2,2-diphenyl-2-n-propoxy)acetoxy]piperidinium iodide 
• 54556-98-8 propiverine hydrochloride 

Relevant academic research and scientific papers

Preparation method of propiverine hydrochloride

The invention relates to a preparation method of propiverine hydrochloride; a compound represented by the formula I and 1-methyl-4-piperidinol are subjected to transesterification, and then are subjected to hydrochlorination to generate the product propiverine hydrochloride. The used raw materials and the reaction route are all simple and easy to obtain. More importantly, through scale-up experiment of the route, the yield and purity of the product obtained by the preparation method are found to have little difference from those of a product obtained in laboratories, and the preparation methodis suitable for industrialized popularization.

ANTICHOLINERGIC NEUROPROTECTIVE COMPOSITION AND METHODS

The present invention relates to a pharmaceutical composition comprising propiverine, trospium or glycopyrrolate; and a non-anticholinergic antiemetic agent. It is also related to a pharmaceutical composition comprising a high dose of solifenacin or a pharmaceutically acceptable salts thereof; and a non-anticholinergic antiemetic agent. Pharmaceutical compositions containing high dose of nsPAChA for use for increasing the AChEI blood concentrations and for combating neurodegeneration are also described. The invention also relates to a method for inducing neuroprotection and combating neurodegeneration in a patient suffering from Alzheimer type dementia as well as to a method for increasing the blood levels of an acetyl choline esterase inhibitor (AChEI) in a human subject treated with an AChEI dose.