60580-41-8

Upstream product

• 94-36-0 dibenzoyl peroxide 
• 69514-42-7 3-(2-bromomethyl-phenyl)-5-phenyl-isoxazole 
• 69514-44-9 [2-(5-phenyl-isoxazol-3-yl)-phenyl]-methanol 
• 65349-28-2 2,3-dibromo-3-phenyl-1-o-tolyl-propan-1-one 
• 536-74-3 phenylacetylene 
• 69053-95-8 o-Metohycarbonylbenzohydroximinoyl chloride 
• 69053-94-7 Methyl 2-(hydroximinomethyl)benzoate 
• 4122-56-9 methyl o-formylbenzoate 
• 83727-26-8 Methyl 2-(5-phenylisoxazol-3-yl)benzoate 
• 65349-23-7 3-(2-methylphenyl)-5-phenylisoxazole 

Downstream Products

• 69643-73-8 (3Z)-3-(2-oxo-2-phenylethylidene)-2,3-dihydro-1H-isoindol-1-one 

Relevant academic research and scientific papers

Iron Promoted Ring Opening and Ring Closing Cascade (ROCC) Reaction of Ortho-Carboxy-Isoxazoles Leading to Isoindolinone Derivatives

An efficient and convenient route for the synthesis of various functionalized 3-alkylidene isoindolin-1-ones is presented. The synthesis involves the ring opening and ring closing cascade (ROCC) reaction of ortho-carboxy-isoxazole using Fe/NH4Cl. This is the first report for the synthesis of 3-alkylidene isoindolin-1-one using Fe/NH4Cl.

Nitrile Oxide Cycloaddtion Routes to 2-(Isoxazolyl)benzoates and 2-(1,2,4-Oxadiazol-3-yl)benzoates

Cycloaddition of aromatic nitrile oxides to methyl o-vinylbenzoate produced methyl 2-(3-aryl-2-isoxazolin-5-yl)benzoates; the isoxazolines were converted to methyl 2-(3-arylisoxazol-5-yl)benzoates.Reaction of the nitrile oxide from o-methoxycarbonylbenzohydroximinoyl chloride (11) with phenylacetylene, styrenes, and aromatic nitriles resulted in methyl 2-(5-phenylisoxazol-3-yl)benzoate, methyl 2-(5-aryl-2-isoxazolin-3-yl)benzoates (15) and methyl 2-(5-aryl-1,2,4-oxadiazol-3-yl)benzoates, respectively.The isoxazolines 15 were converted to the corresponding isoxazoles 16.

Aryl-3-isoxazole benzoates as plant growth regulants and herbicides

2-(5-Aryl or substituted aryl-3-isoxazolyl) benzoic acids or benzoates, e.g., 2-[5-[3-(trifluoromethyl)phenyl]-3-isoxazolyl] benzoic acid, and to their method of use as herbicides and plant growth regulants as well as to agricultural chemical compositions

Isoxazolyl benzamides

This disclosure describes compounds of the formula STR1 where R1 is straight chain alkyl, and R2 is hydrogen, halo having an atomic weight of about 19 to 36, lower alkoxy or trifluoromethyl, Which are useful as minor tranquilizers an