606080-59-5 Usage
Uses
Used in Pharmaceutical Industry:
2-(BOC-AMINO)METHYL-5-FLUORO-BENZOIC ACID serves as a crucial building block for the synthesis of a variety of drugs and biologically active molecules. Its presence of a fluorine atom and a protected amino group allows for the creation of complex molecular structures with potential therapeutic applications.
Used in Organic Synthesis:
In the realm of organic synthesis, 2-(BOC-AMINO)METHYL-5-FLUORO-BENZOIC ACID is utilized as a reagent, contributing to the formation of diverse chemical compounds. Its structural components facilitate targeted reactions that are essential for creating specific organic compounds.
Used in Medicinal Chemistry Research:
2-(BOC-AMINO)METHYL-5-FLUORO-BENZOIC ACID is also employed as a reagent in medicinal chemistry research. It aids scientists in exploring the properties and potential applications of new chemical entities, particularly those with biological activity that could lead to the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 606080-59-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,6,0,8 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 606080-59:
(8*6)+(7*0)+(6*6)+(5*0)+(4*8)+(3*0)+(2*5)+(1*9)=135
135 % 10 = 5
So 606080-59-5 is a valid CAS Registry Number.
606080-59-5Relevant academic research and scientific papers
Copper-catalyzed C-N coupling in the synthesis of integrase inhibitors of immunodeficiency viruses
Lin, Jinguan,Houpis, Ioannis N.,Liu, Renmao,Wang, Youchu,Zhang, Jianqian
, p. 205 - 214 (2014/05/20)
This contribution describes the total synthesis of a complex macrocyclic integrase inhibitor, a key enzyme involved in the infection process of various immunodeficiency viruses. The key transformation of the synthetic strategy was the selective C-N coupling of a sulfonamide to a heteroaryl bromide in the presence of potentially competing amide and carbamate functionalities. The transformation was accomplished with CuI catalysis using bypiridine as the ligand in the presence of base and enabled a convergent approach to the target molecule.