606080-59-5 Usage
General Description
2-(BOC-AMINO)METHYL-5-FLUORO-BENZOIC ACID is a chemical compound with the molecular formula C14H16FNO4. It is a derivative of benzoic acid and contains a fluorine atom and an amino group protected by a BOC group. 2-(BOC-AMINO)METHYL-5-FLUORO-BENZOIC ACID is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and biologically active molecules. It is also used as a reagent in organic synthesis and medicinal chemistry research. Its properties and structure make it a valuable intermediate in the production of a wide range of chemical compounds with potential biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 606080-59-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,6,0,8 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 606080-59:
(8*6)+(7*0)+(6*6)+(5*0)+(4*8)+(3*0)+(2*5)+(1*9)=135
135 % 10 = 5
So 606080-59-5 is a valid CAS Registry Number.
606080-59-5Relevant articles and documents
Copper-catalyzed C-N coupling in the synthesis of integrase inhibitors of immunodeficiency viruses
Lin, Jinguan,Houpis, Ioannis N.,Liu, Renmao,Wang, Youchu,Zhang, Jianqian
, p. 205 - 214 (2014/05/20)
This contribution describes the total synthesis of a complex macrocyclic integrase inhibitor, a key enzyme involved in the infection process of various immunodeficiency viruses. The key transformation of the synthetic strategy was the selective C-N coupling of a sulfonamide to a heteroaryl bromide in the presence of potentially competing amide and carbamate functionalities. The transformation was accomplished with CuI catalysis using bypiridine as the ligand in the presence of base and enabled a convergent approach to the target molecule.
