606095-53-8

Basic information

• Product Name: 3-Quinolinemethanamine,2-chloro-8-methyl-N-(phenylmethyl)-(9CI)
• Synonyms: 3-Quinolinemethanamine,2-chloro-8-methyl-N-(phenylmethyl)-(9CI);Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine
• CAS NO: 606095-53-8
• Molecular Formula: C₁₈H₁₇ClN₂
• Molecular Weight: 296.79398
• Product Categories: QUINOLINE
• Mol File: 606095-53-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Quinolinemethanamine,2-chloro-8-methyl-N-(phenylmethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Quinolinemethanamine,2-chloro-8-methyl-N-(phenylmethyl)-(9CI)(606095-53-8)
• EPA Substance Registry System: 3-Quinolinemethanamine,2-chloro-8-methyl-N-(phenylmethyl)-(9CI)(606095-53-8)

Safety Data

• Hazardous Substances Data: 606095-53-8(Hazardous Substances Data)

Upstream product

• 948291-50-7 2-chloro-3-(chloropmethyl)-8-methylquinoline 
• 100-46-9 benzylamine 
• 73568-26-0 2-chloro-8-methyl-quinoline-3-carbaldehyde 
• 1421699-11-7 C₁₈H₁₅ClN₂ 
• 333408-31-4 2-chloro-3-(hydroxymethyl)-8-methylquinoline 

Relevant articles and documents

Intramolecular Heck reaction: A facile sequential one-pot synthesis of 1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridines

A simple and convenient sequential one-pot synthesis of 1,2,3,4-tetrahydrobenzo[b][1,6] naphthyridines has been developed. The reductive amination of 2-chloro-3-formylquinolines with various amines in the presence of sodium borohydride provided the corresponding secondary amines in high yields. Further, a sequential one-pot reaction involving N-allylation and intramolecular Heck type 6-exo-trig cyclization was performed on the secondary amines to afford a range of desired 1,2,3,4-tetrahydrobenzo[b][1,6]-naphthyridine derivatives in good to high yields.