60631-76-7Relevant articles and documents
Asymmetric diels-alder reactions of α,β-unsaturated aldehydes catalyzed by a diarylprolinol silyl ether salt in the presence of water
Hayashi, Yujiro,Samanta, Sampak,Gotoh, Hiroaki,Ishikawa, Hayato
supporting information; experimental part, p. 6634 - 6637 (2009/03/12)
(Chemical Equation Presented) Water, water, everywhere: The title reaction predominantly affords the exo isomer with excellent enantioselectivity (see scheme; TMS=trimethylsilyl). The synthesis can be carried out without organic solvents and provides the products by distillation. Water increases the rate and enantioselectivity of the reaction.