60644-67-9Relevant academic research and scientific papers
Synthesis of taiwaniaquinoids via Nazarov triflation
Liang, Guangxin,Xu, Yue,Seiple, Ian B.,Trauner, Dirk
, p. 11022 - 11023 (2007/10/03)
A unified approach toward the taiwaniaquinoids that has yielded four natural products is described. A new variant of the Nazarov reaction with concomitant formation of an enol triflate serves as one of the key steps, considerably shortening the synthetic
Synthesis of 4-Benzoyl-4-methylcyclohexa-2,5-dienone and its Benzoyl Substitued Derivatives: Isolated 4-Acylcyclohexa-2,5-dienones
Jackson, Lorraine B.,Waring, Anthony J.
, p. 1791 - 1798 (2007/10/02)
The synthesis are reported of 4-benzoyl-4-methylcyclohexa-2,5-dienone, and its 4-(4-chlorobenzoyl) and 4-(4-methoxybenzoyl) analogues.These are the first isolated 4-acylcyclohexa-2,5-dienones containing the dienone function in a monocyclic ring system.All are sensitive to nucleophilic attack at the benzoyl carbonyl group, being cleaved to 4-methylphenol and its derivatives of the appropriate substitued benzoic acid.Treatment with acids failed to give the desired dienone-phenol rearrangement, with a benzoyl migration from C-4 to C-3, but instead gave 4-methylphenyl benzoate or its derivatives, by a reversal of a Fries rearrangement with C-4 to O-aroyl migration.
Behavior of Carbonyl Ylide Generated from 3-Chloro-3-(p-nitrophenyl)diazirine and Acetone. 1,3-Dipolar Cycloaddition to Benzaldehyde and Epoxide Formation
Ibata, Toshikazu,Toyoda, Jiro,Liu, Michael T. H.
, p. 2135 - 2138 (2007/10/02)
A carbonyl ylide generated from 3-chloro-3-(p-nitrophenyl)diazirine and acetone either 1,3-dipolar cycloadds to benzaldehydes to afford 2,2-dimethyl-4-aryl-5-(p-nitrophenyl)dioxole or intramolecularly cyclizes to give 2-chloro-2-methyl-3-(p-nitrophenyl)-3
