607-69-2

Basic information

• Product Name: 2-CHLORO-4-HYDROXYQUINAZOLINE
• Synonyms: 2-CHLORO-4-HYDROXYQUINAZOLINE;2-chloroquinazolin-4-ol;4(3H)-Quinazolinone, 2-chloro-;2-Chloro-4(1H)-quinazolinone;2-Chloroquinazolin-4-one;2-Chloroquinazolin-4(3H)
• CAS NO: 607-69-2
• Molecular Formula: C₈H₅ClN₂O
• Molecular Weight: 180.59
• Mol File: 607-69-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 218-220℃
• Boiling Point: 325.9 °C at 760 mmHg
• Flash Point: 150.9 °C
• Appearance: /
• Density: 1.50
• Vapor Pressure: 0.000223mmHg at 25°C
• Refractive Index: 1.688
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.12±0.20(Predicted)
• CAS DataBase Reference: 2-CHLORO-4-HYDROXYQUINAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-HYDROXYQUINAZOLINE(607-69-2)
• EPA Substance Registry System: 2-CHLORO-4-HYDROXYQUINAZOLINE(607-69-2)

Safety Data

• Hazardous Substances Data: 607-69-2(Hazardous Substances Data)

Usage

Description

2-CHLORO-4-HYDROXYQUINAZOLINE is a chlorinated derivative of 4-hydroxyquinazoline, a chemical compound within the quinazoline class of organic compounds. It is recognized for its potential as an antitumor agent and has demonstrated promising results in inhibiting the growth of cancer cells. Furthermore, it has been investigated for its antimicrobial and antiviral properties, positioning it as a versatile compound with broad applications in the pharmaceutical industry for the synthesis of drugs and biologically active compounds.

Uses

Used in Pharmaceutical Industry:
2-CHLORO-4-HYDROXYQUINAZOLINE is used as a key intermediate in the synthesis of various drugs and biologically active compounds due to its unique chemical structure and potential therapeutic properties.
Used in Antitumor Applications:
2-CHLORO-4-HYDROXYQUINAZOLINE is used as an antitumor agent for its potential to inhibit the growth of cancer cells, making it a candidate for further research and development in oncology.
Used in Antimicrobial Applications:
2-CHLORO-4-HYDROXYQUINAZOLINE is used as an antimicrobial agent, given its potential to combat microbial infections, which could lead to the development of new antibiotics.
Used in Antiviral Applications:
2-CHLORO-4-HYDROXYQUINAZOLINE is used as an antiviral agent, showing promise in inhibiting viral replication and activity, which could contribute to the creation of new antiviral medications.

InChI:InChI=1/C8H5ClN2O/c9-8-10-6-4-2-1-3-5(6)7(12)11-8/h1-4H,(H,10,11,12)

Upstream product

• 124-48-1 chlorodibromomethane 
• 28144-70-9 anthranilic acid amide 
• 120-94-5 1-Methylpyrrolidine 
• 86-96-4 1,2,3,4-tetrahydro-quinazoline-2,4-dione 

Downstream Products

• 607-68-1 2,4-dichloroquinazoline 
• 940907-93-7 2-((2-(3-aminopiperidin-1-yl)-4-oxoquinazolin-3(4H)-yl)methyl)benzonitrile 
• 873107-36-9 C₂₂H₂₅ClN₄O₂ 
• 1022-45-3 2-phenyl-4(3H)-quinazolinone 
• 22587-11-7 2-(piperazin-1-yl)quinazolin-4(3H)-one 
• 76005-47-5 2-<<4-(diethylamino)cyclohexyl>amino>-4-quinazolinol 
• 345229-18-7 2-<<4-dimethylamino)cyclohexyl>amino>-4-quinazolinol 

Relevant articles and documents

NOVEL COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

Disclosed are a compound for an organic electroluminescent device, and an organic electroluminescent device comprising the same. Accordingly, provided is a compound for an organic electroluminescent device, which can be used as a host and a hole transport material having excellent electrical stability and hole transporting capability and improving light emitting efficiency of a phosphorescent material by having a high triplet energy. An organic electroluminescent device is also provided. The compound for an organic electroluminescent device is represented by structural formula 1.COPYRIGHT KIPO 2016