60710-40-9

Usage

Uses

Used in Organic Synthesis:
4-(Benzyloxy)-2-bromo-1-methylbenzene is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows for further chemical reactions and modifications, contributing to the development of new compounds with specific properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(Benzyloxy)-2-bromo-1-methylbenzene is utilized as a starting material or intermediate in the synthesis of pharmaceuticals. Its potential biological activity and reactivity make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Materials Science:
4-(Benzyloxy)-2-bromo-1-methylbenzene may also have applications in the field of materials science. Its chemical properties could be harnessed to create new materials with specific characteristics, such as improved stability, reactivity, or other desirable traits.
Used as a Reagent in Organic Chemical Reactions:
In addition to its role as a building block and intermediate, 4-(Benzyloxy)-2-bromo-1-methylbenzene can be employed as a reagent in various organic chemical reactions. Its reactivity allows it to participate in a range of processes, facilitating the synthesis of target compounds and contributing to the advancement of organic chemistry.
Overall, 4-(Benzyloxy)-2-bromo-1-methylbenzene is a versatile chemical compound with potential applications in organic synthesis, pharmaceutical research, materials science, and as a reagent in organic chemical reactions. Its unique structure and properties make it of interest to researchers and chemists in various fields.

Upstream product

• 6627-55-0 2-bromo-p-cresol 
• 100-44-7 benzyl chloride 
• 60710-39-6 3-bromo-p-cresol 
• 100-39-0 benzyl bromide 

Downstream Products

• 60710-42-1 4-Benzoloxybenzaldehyd-2-T 
• 60710-44-3 4-Benzyloxy-β-nitrostyrol-2-T 
• 60710-46-5 4-Benzyloxybenzyl-2-T-alkohol 
• 60710-47-6 4-Benzyloxybenzyl-2-T-chlorid 
• 60710-43-2 4-Benzyloxybenzoesaeure-2-T 
• 60710-48-7 Diethyl-(4-benzyloxybenzyl-2-T)-acetamidomalonat 
• 60710-45-4 2-(4-Benzyloxyphenyl-2-T)-ethylamin 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of novel dual FFA1 and PPARδ agonists possessing phenoxyacetic acid scaffold

The free fatty acid receptor 1 (FFA1/GPR40) and peroxisome proliferator-activated receptor δ (PPARδ) have been widely considered as promising targets for type 2 diabetes mellitus (T2DM) due to their respective roles in promoting insulin secretion and impr

BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME

Provided is a compound showing excellent antifungal activity against Trichophyton fungus, which is a major causative microorganism of superficial mycosis, and high effectiveness on diseases caused by Trichophyton fungi. A biaryl derivative represented by the formula (I) or a salt thereof: wherein ring A is an optionally substituted phenyl, or an optionally substituted 5- or 6-membered ring heteroaryl (ring A may be further condensed to form an optionally substituted fused ring); Q is CH2, C=O, NH, O, S or the like; X1, X2 and X3 are CR1 or N; Y is CH or N; Z is CR2b or N; R2a and R2b are each a hydrogen atom, a halogen atom, an optionally substituted C1-C6 alkyl group, a C1-C6 haloalkyl group or the like; R2a and R2b may form, together with carbon atoms bonded thereto, an optionally substituted carbocycle, or an optionally substituted heterocycle.

PHARMACEUTICALS COMPRISING BIARYL DERIVATIVES OR SALTS THEREOF

PROBLEM TO BE SOLVED: To provide compounds with excellent antimycotic activity against Trichophyton. SOLUTION: The invention provides pharmaceuticals comprising biaryl derivatives represented by general formula (I) or salts thereof, where ring A is optionally substituted phenyl or the like; Q is CH2 or the like; X1, X2 and X3 are CR1 or the like; and Y is CH or N. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Enantioselective Rh-Catalyzed Carboacylation of C=N Bonds via C-C Activation of Benzocyclobutenones

Herein we describe the first enantioselective Rh-catalyzed carboacylation of oximes (imines) via C-C activation. In this transformation, the benzocyclobutenone C1-C2 bond is selectively activated by a low valent rhodium catalyst and subsequently the resulting two Rh-C bonds add across a C=N bond, which provides a unique approach to access chiral lactams. A range of polycyclic nitrogen-containing scaffolds were obtained in good yields with excellent enantioselectivity. Further derivatization of the lactam products led to a rapid entry to various novel fused heterocycles.