607361-16-0

Basic information

• Product Name: Benzene, 1-(1,1-dimethylethyl)-4-[(1E)-2-(4-methoxyphenyl)ethenyl]-
• CAS NO: 607361-16-0
• Molecular Formula: C19H22O
• Molecular Weight: 266.383
• Mol File: 607361-16-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1,1-dimethylethyl)-4-[(1E)-2-(4-methoxyphenyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1,1-dimethylethyl)-4-[(1E)-2-(4-methoxyphenyl)ethenyl]-(607361-16-0)
• EPA Substance Registry System: Benzene, 1-(1,1-dimethylethyl)-4-[(1E)-2-(4-methoxyphenyl)ethenyl]-(607361-16-0)

Safety Data

• Hazardous Substances Data: 607361-16-0(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 1746-23-2 4-tert-Butylstyrene 
• 637-69-4 4-Methoxystyrene 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 123324-71-0 p-tert-butylphenylboronic acid 
• 1366392-17-7 (E)-1-(tert-butyl)-4-(2-iodovinyl)benzene 
• 104-94-9 4-methoxy-aniline 
• 6303-59-9 (E)-4-(2-bromo-vinyl)-anisole 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 118578-89-5 diethyl (4-tert-butyl)benzylphosphonate 

Downstream Products

• 677353-68-3 (E)-4-tert-butyl-4'-hydroxystilbene 
• 1435912-93-8 C₁₉H₂₂O 

Relevant articles and documents

Pd-Catalyzed Cross-Coupling of Organostibines with Styrenes to Give Unsymmetric (E)-Stilbenes and (1 E,3 E)-1,4-Diarylbuta-1,3-dienes and Fluorescence Properties of the Products

A general and effective palladium-catalyzed cross-coupling of organostibines with styrenes to give (E)-olefins was disclosed. By the use of an organostibine reagent, this method can produce unsymmetric (E)-1,2-diarylethylenes and (1E,3E)-1,4-diarylbuta-1,3-dienes in good yields with high E/Z selectivity and good functional group tolerance. Resveratrol and DMU-212 were synthesized in high yield. The protocol can be extended to the synthesis of (1E,3E,5E)-1,6-diphenylhexa-1,3,5-triene in 40% yield. Products 5e, 5f, and 7a showed good photoluminescence quantum yields ranging from 72 to 99%.

Transition-Metal-Free Matsuda-Heck Type Cross-Coupling and Mechanistic Evidence for a Radical Mechanism

The Matsuda-Heck reaction, usually performed with palladium catalysts, can be carried out under transition-metal-free conditions in the presence of a KOtBu/DMF couple. This system allows the selective and direct synthesis of stilbenes from aryldiazonium salts under mild temperature (20 °C). Mechanistic studies suggest a radical pathway in which the DMF acts as the initiator of the overall process.

Preparation of Vinyl Arenes by Nickel-Catalyzed Reductive Coupling of Aryl Halides with Vinyl Bromides

This work emphasizes the synthesis of substituted vinyl arenes by reductive coupling of aryl halides with vinyl bromides under mild and easy-to-operate nickel-catalyzed reaction conditions. A broad range of aryl halides, including heteroaromatics, and vinyl bromides were employed to yielding products in moderate to excellent yields with high functional-group tolerance. The nickel-catalytic system displays good chemoselectivity between the two C(sp2)-halide coupling partners, thus demonstrating a mechanistic pathway distinct from other stepwise protocols.