858345-18-3

Basic information

• Product Name: 2,3-di-O-palmitoyl-1-O-(4'-methoxyphenyl)-sn-glycerol
• Synonyms: 2,3-di-O-palmitoyl-1-O-(4'-methoxyphenyl)-sn-glycerol
• CAS NO: 858345-18-3
• Molecular Weight: 675.046
• Mol File: 858345-18-3.mol

Chemical Properties

• CAS DataBase Reference: 2,3-di-O-palmitoyl-1-O-(4'-methoxyphenyl)-sn-glycerol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-di-O-palmitoyl-1-O-(4'-methoxyphenyl)-sn-glycerol(858345-18-3)
• EPA Substance Registry System: 2,3-di-O-palmitoyl-1-O-(4'-methoxyphenyl)-sn-glycerol(858345-18-3)

Safety Data

• Hazardous Substances Data: 858345-18-3(Hazardous Substances Data)

Upstream product

• 142037-06-7 (R)-1-Chloro-3-(4-methoxy-phenoxy)-propan-2-ol 
• 2211-94-1 (2S)-2-{[4-(methoxy)phenoxy]methyl}oxirane 
• 17131-52-1 (S)-1-O-(4-methoxyphenyl)glycerol 
• 57-10-3 1-hexadecylcarboxylic acid 

Downstream Products

• 6076-30-8 1,2-di-O-palmitoyl-sn-glycerol 

Relevant articles and documents

4(2)-Methoxyphenyl glycerol ethers in the synthesis of nonracemic di-O,O-acylglycerols

Effective methods for the synthesis of nonracemic 4-and 2-methoxyphenyl glycerol ethers from nonracemic 3-chloropropanediols and by direct resolution of the racemate, respectively, were developed. Some existing discrepancies related to the to chiroptical properties of their derivatives were eliminated. Both ethers were used to synthesize nonracemic 3-O-aryloxy-1,2-di-O',O'-palmitoyl glycerols.

A facile and convenient chemoenzymatic synthesis of optically active O-(4-methoxyphenyl)-glycidol and 1,2-diacyl-sn-glycerol

A convenient preparation of the (R)- and (S)-enantiomers of O-(4-methoxyphenyl)-glycidol by a one-pot reduction of ketone 3 and in situ lipase mediated resolution is described. Activated moist aluminium oxide in the presence of Pseudomonas cepacia lipase immobilized on ceramic particles (PS-C) has been found effective for the transesterification leading to a high degree of enantioselectivity. These chiral glycidols were further used as a chiral precursor for the synthesis of biologically important 1,2-O-diacyl-sn-glycerol under mild reaction conditions. The present method is facile for the synthesis of chiral glycidols in high enantioselectivity when compared to the previously reported methods.