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4'-Hydroxy-5'-chlor-4-methoxy-chalkon, also known as 4-methoxy-5-chloro-4'-hydroxychalkone, is a synthetic organic compound characterized by its molecular formula C15H11ClO4. 4'-Hydroxy-5'-chlor-4-methoxy-chalkon features a benzopyrone structure, which is a type of flavonoid, with a hydroxyl group at the 4' position, a chlorine atom at the 5' position, and a methoxy group at the 4 position. It is known for its potential applications in pharmaceutical research, particularly in the development of new drugs, due to its unique chemical structure and properties. The compound's specific activity and pharmacological effects are subjects of ongoing scientific investigation, as researchers explore its potential role in various therapeutic areas.

6077-25-4

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6077-25-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6077-25-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,7 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6077-25:
(6*6)+(5*0)+(4*7)+(3*7)+(2*2)+(1*5)=94
94 % 10 = 4
So 6077-25-4 is a valid CAS Registry Number.

6077-25-4Downstream Products

6077-25-4Relevant academic research and scientific papers

Development of pH-activatable fluorescent probes for rapid visualization of metastatic tumours and fluorescence-guided surgeryviatopical spraying

Cao, Wenwen,Li, Xiaoxin,Wu, Peng,Xiong, Hu

, p. 10636 - 10639 (2021/10/19)

A series of pH-activatable aza-BODIPY-based fluorescent probes were developed for rapid cancer visualization and real-time fluorescence-guided surgery by harnessing topical spraying. These probes exhibited good water-solubility, a tunable pKafrom 5.0 to 7.9, and stable intense NIR emission at ～725 nm under acidic conditions.AzaB5with a pKavalue of 6.7 was able to rapidly and clearly visualize pulmonary and abdominal metastatic tumours including tiny metastases less than 2 mmviatopical spraying, further improving intraoperative fluorescence-guided resection. We believe thatAzaB5is promising as a powerful tool to rapidly delineate a broad range of malignancies and assist surgical tumour resection.

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