607713-81-5

Basic information

• Product Name: 4-hydroxy-1-(4-nitrophenyl)butan-1-one
• Synonyms: 4-hydroxy-1-(4-nitrophenyl)butan-1-one
• CAS NO: 607713-81-5
• Molecular Weight: 209.202
• Mol File: 607713-81-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-1-(4-nitrophenyl)butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-1-(4-nitrophenyl)butan-1-one(607713-81-5)
• EPA Substance Registry System: 4-hydroxy-1-(4-nitrophenyl)butan-1-one(607713-81-5)

Safety Data

• Hazardous Substances Data: 607713-81-5(Hazardous Substances Data)

Upstream product

• 605661-31-2 4-{[tert-butyl (dimethyl)silyl]oxy}-1-(4-nitrophenyl)butan-1-one 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 607713-64-4 6-[2-(dimethylamino)ethyl]-5-(4-nitrophenyl)thieno[2,3-d]pyrimidin-4-amine 
• 607713-66-6 5-(4-aminophenyl)-6-[2-(dimethylamino)ethyl]thieno[2,3-d]pyrimidin-4-amine 
• 607713-63-3 2-amino-5-[2-(dimethylamino)ethyl]-4-(4-nitrophenyl)-3-thiophenecarbonitrile 
• 607713-62-2 4-(dimethylamino)-1-(4-nitrophenyl)-1-butanone 
• 866578-97-4 methanesulfonic acid 4-(4-nitrophenyl)-4-oxobutyl ester 

Relevant articles and documents

Microwave-accelerated fluorodenitrations and nitrodehalogenations: expeditious routes to labeled PET ligands and fluoropharmaceuticals

Methods for the expeditious fluorination of arenes have been investigated, using readily available fluoride sources. An optimized procedure for microwave-accelerated fluorodenitration has been developed, giving good to excellent yields in less than 10 min, rendering it practical for use in the preparation of F18 labeled ligands for PET imaging. Application of the method in the synthesis of CNS agents is demonstrated, and a practical method for the preparation of substrates is also presented.