607731-70-4

Upstream product

• 71-43-2 benzene 
• 2051-95-8 succinylbenzene 
• 1821-12-1 4-Phenylbutyric acid 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 117408-90-9 2-iodo-1-phenyl-3,4-dihydronaphthalene 
• 94051-93-1 1-phenyl-1,2,3,4-tetrahydronaphthalen-1-ol 
• 874338-64-4 1-benzyl-3-phenylprop-2-ynyl acetate 
• 7469-40-1 1-phenyl-3,4-dihydronaphthalene 
• 17572-78-0 1,4-diphenylbut-3-yn-1-ol 
• 62969-97-5 1,4-diphenyl-3-butyn-2-ol 

Downstream Products

• 809274-72-4 2-[(4-methoxyphenyl)ethynyl]-1-phenylnaphthalene 
• 206-44-0 fluoranthene 

Relevant academic research and scientific papers

Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons

Convergent synthetic pathways were devised for efficient synthesis of a series of uniformly 13C labeled polycyclic aromatic hydrocarbons de novo from U-13C-benzene and other simple commercially-available 13C-starting compounds. All target products were obtained in excellent yields, including the alternant PAH U-13C-naphthalene, U-13C-phenanthrene, U-13C-anthracene, U- 13C-benz[a]anthracene, U-13C-pyrene and the nonalternant PAH U-13C-fluoranthene.

Synthesis of naphthalenes and 2-naphthols by the electrophilic cyclization of alkynes

A wide variety of substituted naphthalenes are readily prepared regioselectively under mild reaction conditions by the 6-endo-dig electrophilic cyclization of appropriate arene-containing propargylic alcohols by IC1, I 2, Br2, NBS, and PhSeBr. 3-Iodo-2-naphthols have also been prepared in excellent yields by the cyclization of analogous 1-aryl-3-alkyn-2-ones. This methodology readily accommodates various functional groups and has been successfully extended to the synthesis of substituted carbazoles and dibenzothiophenes.

Synthesis of fused polycycles by 1,4-palladium migration chemistry

Novel palladium migration/arylation methodology for the synthesis of complex fused polycycles has been developed, in which one or more sequential Pd-catalyzed intramolecular migration processes involving C-H activation are employed. The chemistry works best with electron-rich aromatics, which is in agreement with the idea that these palladium-catalyzed C-H activation reactions parallel electrophilic aromatic substitution.

1,4-Palladium migration via C-H activation, followed by arylation: Synthesis of fused polycycles

A novel palladium migration/arylation methodology for the synthesis of complex fused polycycles has been developed, in which one or more sequential Pd-catalyzed intramolecular migration processes involving C-H activation are employed. The chemistry works best with electron-rich aromatics, which is in agreement with the idea that these palladium-catalyzed C-H activation reactions parallel electrophilic aromatic substitution. Copyright