607738-08-9

Upstream product

• 100-39-0 benzyl bromide 

Downstream Products

• 87326-77-0 methyl 3-O-benzyl-α-L-idopyranuronate 
• 444118-44-9 methyl 3-O-benzyl-1,2-O-isopropylidene-β-L-idopyranosyluronate 
• 1227467-78-8 methyl 3-O-benzyl-4-O-levulinyl-L-idopyranuronate 
• 1262887-40-0 C₃₅H₄₂O₉Si 
• 1262887-41-1 C₄₂H₄₆O₁₀Si 
• 1262887-42-2 C₂₆H₂₈O₁₀ 
• 1262887-43-3 C₂₈H₂₈Cl₃NO₁₀ 
• 607738-12-5 3,6-di-O-benzyl-1,2-O-isopropylidene-β-D-mannofuranose 
• 607738-15-8 3,6-di-O-benzyl-1,2-O-isopropylidene-β-D-lyxo-hexofuranos-5-ulose 
• 607738-10-3 5,6-anhydro-3-O-benzyl-1,2-O-isopropylidene-β-D-mannofuranose 

Relevant academic research and scientific papers

AN EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM

The present invention relates to a process for the synthesis of the Factor Xa anticoagulent Fondaparinux and related compounds. The invention relates, in addition, to efficient and scalable processes for the synthesis of various intermediates useful in the synthesis of Fondaparinux and related compounds.

Stereoselectivity in deoxygenation of 5-hydroxy-5-phosphinyl-hexofuranoses (α-hydroxyphosphonates)

The addition of dimethyl phosphonate to six different hexofuranos-5-uloses in the presence of DBU, followed by esterification with methoxalyl chloride and then radical reduction, afforded 5-deoxy-5-dimethoxyphosphinyl-D- and L-hexofuranoses. The stereosel