608142-28-5Relevant academic research and scientific papers
THIOPHENE DERIVATIVES
-
Page/Page column 25, (2012/04/17)
Disclosed is a compound of formula (1), wherein R1, R2, R3, R4, R5, R6, R7 and R8 are as defined in the present application.
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate, also known as (R)-Apremilast (A729705), is an enantiomer of Apremilast (A729700). It is an intermediate compound in the synthesis process of Apremilast, which is an oral phosphodiesterase 4 (PDE4) inhibitor. (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate plays a crucial role in the development of medications for various inflammatory and autoimmune diseases.
608142-28-5
Post Buying Request-
-
Basic information
- Product Name: (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate
- Synonyms: (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate
- CAS NO:608142-28-5
- Molecular Formula: C8H15NO3*C12H19NO4S
- Molecular Weight: 446.55816
- EINECS: N/A
- Product Categories: N/A
- Mol File: 608142-28-5.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate(CAS DataBase Reference)
- NIST Chemistry Reference: (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate(608142-28-5)
- EPA Substance Registry System: (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate(608142-28-5)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 608142-28-5(Hazardous Substances Data)
608142-28-5 Suppliers
Recommended suppliers
608142-28-5 Usage
Uses
Used in Pharmaceutical Industry:(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate is used as an intermediate in the synthesis of Apremilast, an oral PDE4 inhibitor, for the treatment of psoriatic arthritis. Apremilast has shown efficacy in reducing the signs and symptoms of psoriatic arthritis, as well as improving physical function and quality of life for patients.
Additionally, Apremilast has been studied for its potential use in treating other inflammatory and autoimmune conditions, such as Crohn's disease, ulcerative colitis, and multiple sclerosis. (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate's role as an intermediate in the synthesis of Apremilast makes it a valuable component in the development of these potential treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 608142-28-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,8,1,4 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.Calculate Digit Verification of CAS Registry Number 608142-28:
(8*6)+(7*0)+(6*8)+(5*1)+(4*4)+(3*2)+(2*2)+(1*8)=135
135 % 10 = 5
So 608142-28-5 is a valid CAS Registry Number.
608142-28-5Upstream product
608142-28-5Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 608142-28-5
(R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate
