60835-90-7

Usage

Uses

Used in Pharmaceutical Industry:
1-bromo-4-(2-methoxyethyl)benzene is utilized as an intermediate in the production of pharmaceuticals, contributing to the synthesis of a range of medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 1-bromo-4-(2-methoxyethyl)benzene is employed as an intermediate for the synthesis of various agrochemicals, playing a role in the development of products for agricultural applications.
Used in Organic Synthesis:
1-bromo-4-(2-methoxyethyl)benzene is used as a building block in organic synthesis, enabling the creation of more complex chemical structures for a variety of purposes.
Used as a Solvent:
1-bromo-4-(2-methoxyethyl)benzene functions as a solvent in certain organic reactions, facilitating processes that require the dissolution of specific substances.
Used as a Reagent:
1-bromo-4-(2-methoxyethyl)benzene also serves as a reagent in organic chemistry, participating in reactions that lead to the formation of desired products.
Safety Considerations:
Due to its flammability and potential to cause skin and eye irritation, 1-bromo-4-(2-methoxyethyl)benzene should be handled and stored with appropriate care to mitigate any hazards associated with its use.

Upstream product

• 4654-39-1 4-bromophenethanol 
• 74-88-4 methyl iodide 
• 41841-16-1 (4-bromo-phenyl)-acetic acid methyl ester 
• 106-37-6 1.4-dibromobenzene 
• 67-56-1 methanol 
• 74-85-1 ethene 
• 6999-03-7 1-bromo-4-(trimethylsilyl)benzene 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 37859-24-8 2-(4-bromophenyl)acetyl chloride 
• 107-30-2 chloromethyl methyl ether 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Downstream Products

• 60835-91-8 4-(2-methoxyethyl)benzoic acid 
• 84803-56-5 4-(2-methoxyethyl)aniline 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 1082066-32-7 2-(4-(2-methoxyethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1450816-85-9 (2E,2'E)-diethyl 3,3'-(5-(methoxycarbonyl)-2-(2-methoxyethyl)-1,3-phenylene)diacrylate 
• 1450816-84-8 (E)-methyl 3-(3-ethoxy-3-oxoprop-1-en-1-yl)-4-(2-methoxyethyl)benzoate 
• 1450816-98-4 methyl 4-(2-methoxyethyl)benzoate 
• 60835-87-2 4-(β-Methoxyethyl)-benzoesaeure-methyl-d3-ester 

Relevant academic research and scientific papers

Oxidative 1,2-Difunctionalization of Ethylene via Gold-Catalyzed Oxyarylation

Under the conditions of oxidative gold catalysis, exposure of ethylene to aryl silanes and alcohols generates products of 1,2-oxyarylation. This provides a rare example of a process that allows catalytic differential 1,2-difunctionalization of this feedstock chemical.

GLP-1 RECEPTOR MODULATORS

Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where "^^^^" represents either or both the R and S form of the compound) (I) where A, B, C, Y1, Y2, Z, R1, R2, R3, R4, R5, W1, n, p and q are as defined herein.

OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS

This invention pertains generally to treating bacterial infections using organic compounds of Formula I. In certain aspects, the invention pertains to treating infections caused by Gram-negative bacteria. (I) wherein X, Y, R1, R2, R3, R4 and R5 and defined herein.

Ether-directed ortho-C-H olefination with a palladium(II)/monoprotected amino acid catalyst

Weak coordination is powerful! A PdII-catalyzed olefination of ortho-C-H bonds of arenes directed by weakly coordinating ethers is developed by using monoprotected amino acid (MPAA) ligands. This finding provides a method for chemically modifying ethers, which are abundant in natural products and drug molecules. HFIP=hexafluoroisopropanol. Copyright

Synthesis of ethers from esters via Fe-catalyzed hydrosilylation

Triiron dodecacarbonyl allows for the selective reduction of esters into the corresponding ethers. This protocol has a wide substrate scope. In addition, cholesteryl pelarogonate has been reduced under the reaction conditions with an excellent yield.

Direct reduction of esters to ethers with an indium(III) bromide/triethylsilane catalytic system

An indium(III) bromide-triethylsilane reagent system promotes direct reduction of esters to produce the corresponding unsymmetrical ethers. This simple catalytic system accommodated other carbonyl compounds, such as a tertiary amide and a carboxylic acid. Georg Thieme Verlag Stuttgart.

THIENOPYRIDINE DERIVATIVES

The present invention provides a compound promoting osteogenesis. The present invention provides a compound having the following general formula (I) wherein R 1 is H or alkyl, R 2 is R a S-, R a O-, R a NH-, R a (R b )N- or cyclic amino, and R a and R b are alkyl which may be substituted, cycloalkyl which may be substituted, or the like, or a pharmacologically acceptable salt thereof.

An efficient one-pot synthesis of unsymmetrical ethers: A directly reductive deoxygenation of esters using an InBr3/Et3SiH catalytic system

(Chemical Equation Presented) This study describes a novel one-pot procedure for a directly reductive conversion of the carbonyl function of esters to the corresponding ethers by Et3SiH in the presence of a catalytic amount of InBr3.

Anilide derivative, production and use thereof

This invention is to provide a compound of the formula: wherein R1is an optionally substituted 5- to 6-membered ring; the ring A is an optionally substituted 6- to 7-membered ring; the ring B is an optionally substituted benzene ring; n is an integer of 1 or 2; Z is a chemical bond or a divalent group; R2is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, (2) an optionally substituted nitrogen-containing heterocyclic ring group which may contain a sulfur atom or an oxygen atom as ring constituting atoms and wherein a nitrogen atom may form a quaternary ammonium, (3) a group binding through a sulfur atom or (4) a group of the formula: ?wherein k is 0 or 1, and when k is 0, a phosphorus atom may form a phosphonium; and R5and R6are independently an optionally substituted hydrocarbon group, an optionally substituted hydroxy group or an optionally substituted amino group, and R5and R6may bind to each other to form a cyclic group together with the adjacent phosphorus atom, or a salt thereof , which is useful for antagonizing CCR5 and also for the prevention and treatment of infectious disease of HIV.

Reduction of carboxylic esters to ethers with triethyl silane in the combined use of titanium tetrachloride and trimethylsilyl trifluoromethanesulfonate

Aliphatic acyclic and cyclic ethers are prepared on treatment of their corresponding carboxylic esters and lactones with triethylsilane in the presence of titanium tetrachloride and trimethylsilyl trifluoromethanesulfonate.