60846-23-3

Upstream product

• 40994-22-7 (6R)-3-acetoxymethyl-7t-amino-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; sodium salt 
• 207725-19-7 (2-Amino-thiazol-4-yl)-[(Z)-methoxyimino]-acetic acid 4,6-dimethoxy-[1,3,5]triazin-2-yl ester 
• 63527-52-6 cefotaxime 
• 80756-85-0 (Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate 
• 31461-04-8 (6R,7R)-Trimethylsilyl 7-(Trimethylsilyl)amino-3-acetoxy methylceph-3-em-4-carboxylate 

Downstream Products

• 217803-89-9 1-(isopropoxycarbonyloxy)ethyl 7β-<2-(2-aminothiazol-4-yl)-(Z)-methoxyiminoacetamido>-3-acetoxymethyl-3-cephem-4-carboxylate 
• 121020-94-8 desacetylcefotaxime 

Relevant academic research and scientific papers

2-chloro-4,6-dimethoxy-1,3,5-triazine: A new effective and convenient coupling reagent for cephalosporin derivatives

Chloro-4,6-dimethoxy-1,3,5-triazine(CDMT) 2 was reacted with 2-(2- amino-4-thiazolyl)-2-syn-alkoxyiminoacetic acid 1 to give an active ester intermediate 3.

Cefotaxime sodium pharmaceutical preparation in the transabdominal or vaginal hysterectomy, gastrointestinal tract and genital tract such as the prevention of infection before the application (by machine translation)

The present invention provides a head spore sai wowo sodium or its composition, preparation method, preparation and use. The head spore sai wowo sodium or its composition of active ingredients in the Cefotaxime quality content is 98% or more, the impurity content is low, and the safety is high. The present invention provides the preparation method AE - active thioester and 7 - ACA reaction to obtain the spore saisai wo acid; with the spore saisai wo acid generating sodium salt, can get [...]. The preparation method is simple, stable and reliable, production process stability is strong. Therefore, the head spore sai wowo sodium or its composition can be used for pharmaceutical use, particularly for the treatment of transvaginal/abdominal hysterectomy, gastrointestinal, genitourinary tract before and postoperative infection prevention of infection. (by machine translation)