608525-89-9Relevant academic research and scientific papers
New four-component condensations leading to 2,4,5-trisubstituted oxazoles
Wang, Qunzhao,Ganem, Bruce
, p. 6829 - 6832 (2003)
A one-pot reaction leading to the title compounds has been developed based on the in situ acylation and hydroxyarylation of 5-aminooxazoles at the 4-position of the heterocycle.
A general synthesis of 2-substituted-5-aminooxazoles: Building blocks for multifunctional heterocycles
Wang, Qunzhao,Xia, Qian,Ganem, Bruce
, p. 6825 - 6827 (2007/10/03)
Condensation of unsubstituted isocyanoacetamides with aldehydes and ketones, or their derived iminium ions, leads to 2-substituted-5-aminooxazoles, which are useful compounds for drug discovery programs.
