60893-68-7

Upstream product

• 99-76-3 methyl 4-hydroxylbenzoate 
• 6482-24-2 2-Bromoethyl methyl ether 
• 3204-73-7 4-(2-hydroxyethoxy)benzoic acid methyl ester 
• 74-88-4 methyl iodide 
• 17178-10-8 2-methoxy-ethyl p-toluenesulfonyloxy ester 
• 109-86-4 2-methoxy-ethanol 
• 627-42-9 2-chloroethyl methyl ether 

Downstream Products

• 697305-88-7 methyl 4-(2-methoxyethoxy)-3-nitrobenzoate 
• 904298-64-2 4-(2-methoxyethoxy)benzohydrazide 
• 27890-92-2 4-(2-methoxy-ethoxy)-benzoic acid 
• 1429526-44-2 4-{(1E)-3-[(6-chlorohexyl)oxy]-3-oxoprop-1-enyl}phenyl 4-(2-methoxyethoxy)benzoate 
• 1429526-45-3 6-{[(2E)-3-(4-{[4-(2-methoxyethoxy)benzoyl]oxy}phenyl)prop-2-enoyl]oxy}hexyl 3,5-dinitrobenzoate 
• 79407-30-0 [4-(2-methoxyethoxy)phenyl]methanol 
• 79407-31-1 1-(chloromethyl)-4-(2-methoxyethoxy)benzene 

Relevant academic research and scientific papers

COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS

The present invention relates to pharmaceutical agents administered to a subject either in combination or in series for the treatment of a Respiratory Syncytial Virus (RSV) infection, wherein treatment comprises administering a compound effective to inhibit the function of the RSV and an additional compound or combinations of compounds having anti-RSV activity.

C-3 NOVEL TRITERPENONE WITH C-17 REVERSE AMIDE DERIVATIVES AS HIV INHIBITORS

The present invention relates to C-3 novel triterpenone with C-17 reverse amide compounds of Formula (I); and pharmaceutically acceptable salts thereof, wherein ring Formula (II), R1, R2, R3, R4, R5, R6, R7, 'n' and 'm' are as defined in Formula (I). The invention also relates to C-3 novel triterpenone with C-17 reverse amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.

AMINO-PYRROLOPYRIMIDINONE COMPOUNDS AND METHODS OF USE THEREOF

The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (

BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

2-OXO-3,4-DIHYDROPYRIDINE-5-CARBOXYLATES AND THEIR USE

The present invention is directed to novel compounds of Formula (I), pharmaceutically acceptable salts or solvates thereof, and their use.

Reversible control of nanoparticle functionalization and physicochemical properties by dynamic covalent exchange

Existing methods for the covalent functionalization of nanoparticles rely on kinetically controlled reactions, and largely lack the sophistication of the preeminent oligonucleotide-based noncovalent strategies. Here we report the application of dynamic covalent chemistry for the reversible modification of nanoparticle (NP) surface functionality, combining the benefits of non-biomolecular covalent chemistry with the favorable features of equilibrium processes. A homogeneous monolayer of nanoparticle-bound hydrazones can undergo quantitative dynamic covalent exchange. The pseudomolecular nature of the NP system allows for the in situ characterization of surface-bound species, and real-time tracking of the exchange reactions. Furthermore, dynamic covalent exchange offers a simple approach for reversibly switching - and subtly tuning - NP properties such as solvophilicity.

PHOTOALIGNING MATERIALS

The present invention relates to polymer, homo- or copolymer or oligomer for the photoalignment of liquid crystals, especially for the planar orientation of liquid crystals, comprising a main chain and a side chain, wherein the side chain and/or main chain comprises a polar group, compositions thereof, and its use for optical and electro optical devices, especially liquid crystal devices (LCDs).

PHOTOALIGNING MATERIALS

The present invention relates to polymer, homo- or copolymer or oligomer, which, when irradiated with polarised light orients perpendicular to the polarization direction of polarized actinic light, for the photoalignment of liquid crystals, especially for the planar orientation of liquid crystals, and which derives from at least one monomer (I), compositions thereof, and its use for optical and electro optical devices, such as, liquid crystal devices (LCDs), especially for planar orientation of liquid crystals.

Diacylglycerol acyltransferase inhibitors

Provided herein are compounds of the formula (1): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.

Diacylglycerol acyltransferase inhibitors

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.