609367-78-4

Basic information

• Product Name: [(S)-1-(Cyclohexyl-methyl-carbamoyl)-2,2-dimethyl-propyl]-carbamic acid benzyl ester
• CAS NO: 609367-78-4
• Molecular Weight: 360.497
• Mol File: 609367-78-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(S)-1-(Cyclohexyl-methyl-carbamoyl)-2,2-dimethyl-propyl]-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-1-(Cyclohexyl-methyl-carbamoyl)-2,2-dimethyl-propyl]-carbamic acid benzyl ester(609367-78-4)
• EPA Substance Registry System: [(S)-1-(Cyclohexyl-methyl-carbamoyl)-2,2-dimethyl-propyl]-carbamic acid benzyl ester(609367-78-4)

Safety Data

• Hazardous Substances Data: 609367-78-4(Hazardous Substances Data)

Upstream product

• 100-60-7 N-methylcyclohexylamine 
• 62965-10-0 (S)-N-carbobenzoxy-tert-butylleucine 

Downstream Products

• 609367-65-9 (R)-2-[(Benzyloxy-formyl-amino)-methyl]-hexanoic acid [(S)-1-(cyclohexyl-methyl-carbamoyl)-2,2-dimethyl-propyl]-amide 
• 609367-86-4 2-amino-N-cyclohexyl-3,3,N-trimethyl-butyramide 

Relevant articles and documents

Structure-activity relationships of the peptide deformylase inhibitor BB-3497: Modification of the P2′ and P3′ side chains

Structural modifications to the peptide deformylase inhibitor BB-3497 are described. In this paper, we describe the initial SAR around this lead for modifications to both the P2′ and P3′ side chains. Enzyme inhibition and antibacterial activity data revealed that a variety of substituents are tolerated at the P2′ and P3′ positions of the inhibitor backbone. The data from this study highlights the potential for modification at the P2′ and P3′ positions to optimise the physicochemical properties.