60963-18-0Relevant academic research and scientific papers
SUBSTITUTED TRIAZINONES AS THYROID HORMONE RECEPTOR AGONISTS
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, (2021/07/24)
The application relates to a compound of Formula (I') or (I), or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of thyroid hormone receptors, a pharmaceutical composition comprising a compound of Formula (I') or (I), and a method of treating or preventing a disease or disorder regulated by thyroid hormone.
Compound as well as synthesis method and application thereof
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, (2018/12/02)
The invention provides a compound. The compound is characterized by comprising a structure shown in the description. The novel small-molecule compound can be used for promoting regrowth of hair when applied for external use, and can be used for treating a
SELECTIVE TR-BETA 1 AGONIST
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Page/Page column 12, (2010/03/31)
The present invention relates to novel compounds of general formula (I) which are thyroid receptor ligands and are preferably selective for the thyroid hormone receptor beta(TR-Beta). Further, the present invention relates to processes of preparing such c
SELECTIVE TR-BETA 1 AGONIST
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Page/Page column 25, (2008/12/05)
The present invention relates to novel compounds of general formula (I) which are thyroid receptor ligands and are preferably selective for the thyroid hormone receptor beta(TR-Beta). Further, the present invention relates to processes of preparing such c
Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor β (TR-β) selective ligands
Raval, Saurin,Raval, Preeti,Bandyopadhyay, Debdutta,Soni, Krunal,Yevale, Digambar,Jogiya, Digvijay,Modi, Honey,Joharapurkar, Amit,Gandhi, Neha,Jain, Mukul R.,Patel, Pankaj R.
scheme or table, p. 3919 - 3924 (2009/04/07)
Design and synthesis of a novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives are reported and their in vitro thyroid hormone receptor selectivity has been evaluated in the thyroid luciferase receptor assay. The 3-[3,5-dichloro-4-(4-hydroxy-3-isopropylph
