609828-47-9

Upstream product

• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 98391-91-4 (2S,3S)-2,4-dimethylpentane-1,5-diol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 147595-83-3 (2R,3S)-3-<(p-methoxybenzyl)oxy>-2,4-dimethyl-1-phenylsulfonylpentane 
• 147849-63-6 tert-butyl (5R)-3-oxo-5-hydroxy-6-benzyloxyhexanoate 
• 158557-16-5 (2R,3S)-3-<(p-methoxybenzyl)oxy>-2,4-dimethyl-1-phenylthiopentane 
• 549502-23-0 (3S,5R)-6-benzyloxy-3,5-dihydroxy-hexanoic acid tert-butyl ester 
• 380497-27-8 1-[(4S,5S,2R)-5-methyl-4-(methylethyl)(1,3-dioxan-2-yl)]-4-methoxybenzene 
• 380497-28-9 (2S,3S)-3-[(4-methoxyphenyl)methoxy]-2,4-dimethylpentan-1-ol 
• 609828-70-8 Methanesulfonic acid (2S,3S)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyl ester 
• 189069-42-9 (-)-(R)-4-benzyl-3-((2R,3S)-3-hydroxy-2,4-dimethylpentanoyl)oxazolidin-2-one 
• 609828-46-8 tert-butyl (3S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-6-oxohexanoate 
• 609828-44-6 tert-butyl (3S,5S)-3,5-bis(tert-butyldimethylsilyloxy)-6-(phenylmethoxy)hexanoate 

Downstream Products

• 609828-56-0 7-(9-{(1E)(3S,4S)-4-[(4-methoxyphenyl)methoxy]-3,5-dimethylhex-1-enyl}(7S,9R)-6,10-dioxospiro[4.5]dec-7-yl)-1-{9-[(1S)-1-methyl-2-(phenylmethoxy)ethyl](7S,9R)-6,10-dioxaspiro[4.5]dec-7-yl}(4S,6S)-4-hydroxy-6-(tert-butyldimethylsilyloxy)heptan-2-one 
• 1026361-09-0 tert-butyl 2-(9-{(1E)(3S,4S)-4-[(4-methoxyphenyl)methoxy]-3,5-dimethylhex-1-enyl}(7S,9R)-6,10-dioxaspiro[4.5]dec-7-yl)acetate 
• 609828-51-5 2-(9-{(1E)(3S,4S)-4-[(4-methoxyphenyl)methoxy]-3,5-dimethylhex-1-enyl}(7S,9R)-6,10-dioxaspiro[4.5]dec-7-yl)ethanal 

Relevant academic research and scientific papers

Synthesis of the antifungal macrolide antibiotic (+)-roxaticin

The total synthesis of the antifungal macrolide antibiotic roxaticin has been accomplished. The synthesis relies principally on aldol and directed reduction steps to construct the extended 1,3-polyol array present in the natural product. Three principal n