98391-91-4

Upstream product

• 125665-01-2 N-<(2R,3S)-3-hydroxy-2,4-dimethylpentanoyl>bornane-10,2-sultam 
• 74-85-1 ethene 
• 78-84-2 isobutyraldehyde 

Downstream Products

• 158557-15-4 Toluene-4-sulfonic acid (2S,3S)-3-hydroxy-2,4-dimethyl-pentyl ester 
• 113778-76-0 (4S,5S)-4-Isopropyl-2,2,5-trimethyl-[1,3]dioxane 
• 163932-35-2 (2R,3S)-2,4-dimethyl-1-(phenylthio)-3-pentanol 
• 380497-27-8 1-[(4S,5S,2R)-5-methyl-4-(methylethyl)(1,3-dioxan-2-yl)]-4-methoxybenzene 
• 147595-83-3 (2R,3S)-3-<(p-methoxybenzyl)oxy>-2,4-dimethyl-1-phenylsulfonylpentane 
• 158557-16-5 (2R,3S)-3-<(p-methoxybenzyl)oxy>-2,4-dimethyl-1-phenylthiopentane 
• 380497-28-9 (2S,3S)-3-[(4-methoxyphenyl)methoxy]-2,4-dimethylpentan-1-ol 
• 609828-70-8 Methanesulfonic acid (2S,3S)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyl ester 
• 609828-51-5 2-(9-{(1E)(3S,4S)-4-[(4-methoxyphenyl)methoxy]-3,5-dimethylhex-1-enyl}(7S,9R)-6,10-dioxaspiro[4.5]dec-7-yl)ethanal 
• 1026361-09-0 tert-butyl 2-(9-{(1E)(3S,4S)-4-[(4-methoxyphenyl)methoxy]-3,5-dimethylhex-1-enyl}(7S,9R)-6,10-dioxaspiro[4.5]dec-7-yl)acetate 
• 609828-47-9 tert-butyl (6E)(3S,8S,9S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-9-[(4-methoxyphenyl)methoxy]-8,10-dimethyl-undec-6-enoate 
• 609828-56-0 7-(9-{(1E)(3S,4S)-4-[(4-methoxyphenyl)methoxy]-3,5-dimethylhex-1-enyl}(7S,9R)-6,10-dioxospiro[4.5]dec-7-yl)-1-{9-[(1S)-1-methyl-2-(phenylmethoxy)ethyl](7S,9R)-6,10-dioxaspiro[4.5]dec-7-yl}(4S,6S)-4-hydroxy-6-(tert-butyldimethylsilyloxy)heptan-2-one 
• 149157-63-1 (2R,3S)-2,4-dimethyl-3-<(4-methoxybenzyloxy)oxy>pentanal 

Relevant academic research and scientific papers

Domino hydroformylation/enantioselective cross-aldol addition

A domino hydroformylation/enantioselective cross-aldol reaction sequence is reported. Starting from simple alkenes enantiomerically pure aldol addition products, which represent valuable building blocks for polypropionate construction, can be obtained in a one-pot operation.

Bornanesultam-directed asymmetric synthesis of crystalline, enantiomerically pure syn aldols

N-acylsultams 2 furnish, via aldolization of their enolates 16 with aldehydes, diastereomerically pure, crystalline syn aldols. The absolute configuration of the product is controlled by the choice of the enolate counterion: 16, M = B → 3; 16, M = Li or S