609846-23-3Relevant academic research and scientific papers
Cyclopropyl and related analogs of the anti-HIV compound, isodideoxyadenosine
Nair, Vasu,Mickle, Travis,Bera, Sanjib
, p. 239 - 247 (2007/10/03)
Novel 3′-substituted isonucleoside analogs were designed on the basis of the similarities of their electrostatic potential with the active anti-HIV compound, (S, S)-isodideoxy-adenosine. The key synthetic step involved coupling between the dideoxygenated sugar derivatives, 10 and 14, and adenine under Mitsunobu conditions. Anti-HIV data are mentioned.
