609846-24-4

Upstream product

• 59896-06-9 5-O-benzoyl-3-deoxy-1,2-O-isopropylidene-3-C-methyl-α-D-erythro-pentofuranose 
• 59896-02-5 ((3aR,5S,6aR)-2,2-dimethyl-6-methylenetetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 609846-23-3 (2S,3S,4R)-2-benzoyloxymethyl-3-methyltetrahydrofuran-4-ol 
• 66224-66-6 adenine 
• 609846-27-7 Benzoic acid (2S,3R,4R)-4-methanesulfonyloxy-3-methyl-tetrahydro-furan-2-ylmethyl ester 

Relevant academic research and scientific papers

Cyclopropyl and related analogs of the anti-HIV compound, isodideoxyadenosine

Novel 3′-substituted isonucleoside analogs were designed on the basis of the similarities of their electrostatic potential with the active anti-HIV compound, (S, S)-isodideoxy-adenosine. The key synthetic step involved coupling between the dideoxygenated sugar derivatives, 10 and 14, and adenine under Mitsunobu conditions. Anti-HIV data are mentioned.