60988-03-6Relevant academic research and scientific papers
Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies
Mermer, Arif,Faiz, Ozlem,Demirbas, Ahmet,Demirbas, Neslihan,Alagumuthu, Manikandan,Arumugam, Sivakumar
, p. 308 - 318 (2019)
A series of new 1,2,4-triazole and 1,3,4-oxadiazole derivatives was obtained via several steps sequential reactions of phenyl piperazine. Then, these compounds were converted to the corresponding fluoroquinolone hybrids via one pot three component Mannich
Synthesis and tuberculostatic activity of some (4-phenylpiperazin-1- ylmethyl)-1,3,4-oxadiazole and (4-phenylpiperazin-1-ylmethyl)-1,2,4-triazole derivatives
Foks, Henryk,Pancechowska-Ksepko, Danuta,Janowiec, Mieczyslaw,Zwolska, Zofia,Augustynowicz-Kopec, Ewa
, p. 473 - 476 (2007/10/03)
The phenylpiperazineacetic hydrazide cyclization product, 5-(4-phenylpiperazin-1-ylmethyl)-1,3,4-oxadiazole-2-thiol (1) upon alkylation gave the S-methyl derivative (2), next it was transformed into 1-phenyl-4-(5-pyrrolidin-1-yl-1,3,4-oxadiazol-2-ylmethyl
