60998-32-5Relevant academic research and scientific papers
Stilbene synthesis through decarboxylative cross-coupling of substituted cinnamic acids with aryl halides
Rameau, Nelly,Russo, Baptiste,Mangematin, Stéphane,Pinel, Catherine,Djakovitch, Laurent
, p. 132 - 143 (2018)
The Pd-catalyzed decarboxylative cross-coupling reaction between cinnamic acid and aryl iodide derivatives was studied using both homogeneous and heterogeneous Pd-catalysts. It was demonstrated that simple Pd(OAc)2 can catalyze this reaction wi
A SINGLE STEP MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED STILBENES AND ITS ANALOGS
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Page/Page column 14, (2008/06/13)
The present invention relates to a single step, microwave induced process for the preparation of substituted stilbenes and its analogs. Particularly, provides a method for the preparation of commercially important 2- or 4-hydroxy substituted stilbenes in one pot utilizing cheaper substrates in the form of 2- or 4-hydroxy substituted arylaldehyde and/or phenylacetic acids as well as regents in the form of base such as collidine, triethylamine, pyridine, piperidine, sodium acetate, ammonium acetate, imidazole, methyl imidazoles and the like and/or acid such as formic acid, acetic acid, propionic acid and the like for a reaction time varying from lmin-16 hrs depending upon microwave or conventional heating, without using decarboxylating agents with yield varying from 37-66 % depending upon the base and/or acid, solvent and substrate used. It is important to mention that the presence of hydroxy substitution at 2- or 4- position of arylaldehyde and/or aryl acetic acid is essential requirements towards formation of stilbenes in one step.
