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4-Methoxy-2,6-dimethyl phenyl acetonitrile is an organic compound with the chemical formula C11H13NO. It is a derivative of phenyl acetonitrile, featuring a 4-methoxy group and two methyl groups at the 2 and 6 positions on the benzene ring. 4-methoxy-2,6-dimethyl phenyl acetonitrile is characterized by its aromatic structure, with the nitrile group (C≡N) attached to the phenyl ring, which imparts unique chemical properties. It is used in the synthesis of various pharmaceuticals and agrochemicals due to its reactivity and the ability to form stable intermediates in chemical reactions. The compound is also known for its potential applications in the production of dyes and pigments, highlighting its versatility in different industries.

61000-23-5

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61000-23-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 61000-23-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,0,0 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61000-23:
(7*6)+(6*1)+(5*0)+(4*0)+(3*0)+(2*2)+(1*3)=55
55 % 10 = 5
So 61000-23-5 is a valid CAS Registry Number.

61000-23-5Downstream Products

61000-23-5Relevant academic research and scientific papers

THYROID HORMONE RECEPTOR AGONISTS

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Paragraph 252; 253, (2020/05/19)

Provided herein are novel thyroid hormone receptor (TR) agonists, e. g., having Formula I, II, or III. Also provided are methods of preparing the novel TR agonists and method of using the novel TR agonists for treating diseases or disorder modulated by TR agonists, such as NAFLD, NASH, diabetes, hyperlipidemia and/or hypercholesterolemia.

8-(4-Methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazines: Selective and centrally active corticotropin-releasing factor receptor-1 (CRF1) antagonists

Gilligan, Paul J.,He, Liqi,Clarke, Todd,Tivitmahaisoon, Parcharee,Lelas, Snjezana,Li, Yu-Wen,Heman, Karen,Fitzgerald, Lawrence,Miller, Keith,Zhang, Ge,Marshall, Anne,Krause, Carol,McElroy, John,Ward, Kathyrn,Shen, Helen,Wong, Harvey,Grossman, Scott,Nemeth, Gregory,Zaczek, Robert,Arneric, Stephen P.,Hartig, Paul,Robertson, David W.,Trainor, George

scheme or table, p. 3073 - 3083 (2010/01/16)

This report describes the syntheses and structure-activity relationships of 8-(4-methoxyphenyl)pyrazolo-[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF1) receptor antagonists. CRF1 receptor antagonists may be potential anxiolytic or antidepressant drugs. This research culminated in the discovery of analogue 12-3, which is a potent, selective CRF1 antagonist (hCRF1 IC50 ) 4.7 ± 2.0 nM) with weak affinity for the CRF-binding protein and biogenic amine receptors. This compound also has a good pharmacokinetic profile in dogs. Analogue 12-3 is orally effective in two rat models of anxiety: the defensive withdrawal (situational anxiety) model and the elevated plus maze test. Analogue 12-3 has been advanced to clinical trials.

Certain alkylene diamine-substituted pyrazlo (1,5-a)-1,5-pyrimidines and pyrazolo (1,5-a) 1,3,5-triazines

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, (2008/06/13)

Disclosed are compounds of the formula: where R1, R2, R3, R4, R5, R6, and X are defined herein. These compounds are selective modulators of NPY1 receptors. These compounds are useful in the

Amino substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines

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, (2008/06/13)

Disclosed are compounds of the formula: where R1, R2, R3, R4, R5, R6, and X are defined herein. These compounds are selective modulators of NPY1 receptors. These compounds are useful in the

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