61001-12-5Relevant academic research and scientific papers
Synthesis of imidazo[2,1-a]isoquinolines from α-tosyloxyketones and 1-aminoisoquinoline in ionic liquid solvent
Houa, Rei-Sheu,Wang, Huey-Min,Huang, Hsin-Yu,Chen, Ling-Ching
, p. 1417 - 1420 (2007/10/03)
The room temperature ionic liquid n-butylpyridinium tetrafluoroborate (BPyBF4) is used as a 'green' recyclable alternative to classical molecular solvents for the cyclocondensation of α-tosyloxyketones with 1-aminoisoquinoline to prepare imidazo[2,1-a]isoquinolines in good yields.
Regioselective synthesis of 2-arylimidazo[2,1-a] isoquinolines
Weixing,Yongzhou
, p. 320 - 320 (2007/10/03)
Substituted phenacyl bromides react with isoquinoline to form the corresponding quaternary salts which, when heated in ammonium acetate and acetic acid in the presence of Cu(II)O, undergo regioselective cyclisation to give 2-arylimidazo[2,1-a]isoquinoline
Synthesis and pregnancy terminating activity of 2-arylimidazo[2,1-a]isoquinolines and isoindoles
Toja,Omodei Sale,Favara,Omodei-Sale,Cattaneo,Gallico,Galliani
, p. 1222 - 1226 (2007/10/02)
A series of 2-arylimidazo[2,1-a]isoquinolines (1-21), some 5,6-dihydro derivatives (22-28) and 2-phenyl-5H-imidazo[2,1-a]isoindole (29) were synthesized and tested for the pregnancy terminating activity in hamsters and rats. An efficient preparation of 2-
