610300-86-2Relevant academic research and scientific papers
Chiral ligands and their transition metal complexes
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, (2008/06/13)
The present invention relates to chiral phosphorus compounds and their transition metal complexes, and also to the use of these transition metal complexes, especially in asymmetric syntheses.
t-BuOK-mediated hydrophosphination of functionalized alkenes: A novel synthesis of chiral P,N- and P,P-ligands
Bunlaksananusorn, Tanasri,Knochel, Paul
, p. 4595 - 4601 (2007/10/03)
A novel synthesis of effective chiral P,N- and P,P-ligands has been developed by using a t-BuOK-mediated hydrophosphination of chiral alkenylpyridines and alkenylphosphine oxides. Ir complexes of chiral P,N-ligands 1 and 3 gave high enantioselectivities for the hydrogenation of (Z)-α-(acetamido)cinnamate 25 and (E)-1,2-diphenylpropene leading to the hydrogenated products with up to 97% ee.
CHIRAL LIGANDS AND THEIR TRANSITION METAL COMPLEXES
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Page/Page column 24, (2010/02/09)
The invention relates to chiral phosphorus compounds and their transition metal complexes, in addition to the use of said transition metal complexes, in particular in asymmetric syntheses.
New P, N ligands for asymmetric Ir-catalyzed reactions
Bunlaksananusorn, Tanasri,Polborn, Kurt,Knochel, Paul
, p. 3941 - 3943 (2007/10/03)
Chiral Ir complexes such as 1 catalyze the hydrogenation of (E)-1, 2-diphenylpropene at 1 bar of H2 to give (5)-1, 2-diphenylpropane with up to 95% ee and full conversion (see scheme). Methyl (Z)-α -(acetamido)cinnamate underwent enantioselective hydrogenation under similar conditions to the corresponding amino acid derivative with up to 96% ee. BARF = tetrakis(3,5-bis(trifluoromethyl)phenyl)borate, cod = 1, 5-cyclooctadiene.
