61054-28-2Relevant articles and documents
Palladium-Catalyzed Direct C-H Arylation of Isoxazoles at the 5-Position
Shigenobu, Masashi,Takenaka, Kazuhiro,Sasai, Hiroaki
supporting information, p. 9572 - 9576 (2015/08/11)
A palladium-catalyzed direct arylation of isoxazoles with aryl iodides has been achieved. The C-H bond at the 5-position is activated selectively to give coupling products in moderate to good yields. This direct arylation was applied to the synthesis of a spiro-type chiral ligand, which proved to be most effective to the palladium-catalyzed tandem cyclization of a dialkenyl alcohol.
Synthesis of Isomeric Series of Aryltetrahydrobenzisoxazoles and Arylcyclopentisoxazoles
Fos, Empar,Borras, Liset,Gasull, Maria,Mauleon, David,Carganico Germano
, p. 203 - 208 (2007/10/02)
Four series of potential PAF-antagonists in which the isoxazole nucleus is condensed with a polyhydrogenated five- or six-carbon ring were prepared.The synthesis of the compounds 3-aryl-4,5,6,7-tetrahydrobenzisoxazoles 1, 3-arylcyclopentisoxazole 2,