611182-95-7

Basic information

• Product Name: (4-{[tris(propan-2-yl)silyl]oxy}phenyl)methanol
• Synonyms: (4-{[tris(propan-2-yl)silyl]oxy}phenyl)methanol
• CAS NO: 611182-95-7
• Molecular Weight: 280.483
• Mol File: 611182-95-7.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: (4-{[tris(propan-2-yl)silyl]oxy}phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-{[tris(propan-2-yl)silyl]oxy}phenyl)methanol(611182-95-7)
• EPA Substance Registry System: (4-{[tris(propan-2-yl)silyl]oxy}phenyl)methanol(611182-95-7)

Safety Data

• Hazardous Substances Data: 611182-95-7(Hazardous Substances Data)

Usage

Description

(4-[tris(propan-2-yl)silyl]oxyphenyl)methanol, also known as TIPS-OPh alcohol, is a chemical compound characterized by a phenyl ring connected to a silicon atom through an oxy group and a methanol group. It is recognized for its high stability, resistance to harsh reaction conditions, and the ease with which it can be removed under mild conditions, making it a versatile component in organic synthesis.

Uses

Used in Organic Synthesis:
TIPS-OPh alcohol is utilized as a protecting group for alcohols in organic synthesis, providing a means to shield functional groups during chemical reactions, thus preventing unwanted side reactions and ensuring the desired product formation.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TIPS-OPh alcohol is used as a precursor for the synthesis of complex organic compounds, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, TIPS-OPh alcohol serves as a starting material for the creation of various compounds used in the development of pesticides, herbicides, and other agricultural chemicals.
Used in Material Science:
TIPS-OPh alcohol is also employed in material science for the synthesis of silicon-containing polymers and materials, which have potential applications in a range of fields due to their unique properties.
Used in Preparation of Silicon-Containing Materials:
As a useful reagent, TIPS-OPh alcohol is involved in the preparation of silicon-containing materials, which may have applications in areas such as electronics, where such materials can be used in the development of semiconductors or other components.

Upstream product

• 20876-99-7 4-hydroxy-N,N-dimethyl-benzamide 
• 13154-24-0 triisopropylsilyl chloride 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 1085453-61-7 ethyl 4-(triisopropylsilyloxy)benzoate 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 211617-68-4 4-(triisopropylsilyloxy)benzaldehyde 

Downstream Products

• 1145732-90-6 (4-(iodomethyl)phenoxy)triisopropylsilane 
• 1609376-35-3 C₂₄H₃₈O₄Si 
• 1609376-36-4 C₂₄H₃₈O₄Si 
• 1609376-33-1 C₂₁H₂₉BrO₂Si 
• 1609376-34-2 C₂₄H₃₆O₂Si 
• 1609376-31-9 1-phenyl-5-(4-(triisopropylsilyloxy)benzylthio)-1H-tetrazole 
• 1085452-89-6 4-[(5-methyl-3-{3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)methyl]phenol 
• 1269415-94-2 diethyl (4-((triisopropylsilyl)oxy)benzyl)phosphonate 
• 1269171-09-6 C₃₃H₄₂N₂O₅Si 

Relevant articles and documents

Fluorescent probe for fluorine ion detection, application of fluorescent probe and method for detecting fluorine ions in to-be-detected sample

The invention belongs to the technical field of analytical chemistry, and particularly relates to a fluorescent probe for fluorine ion detection, application of the fluorescent probe and a method for detecting fluorine ions in a to-be-detected sample. The invention provides a compound as shown in a formula I, or an optical isomer or salt thereof, and provides application of the compound as a fluorine ion detection fluorescent probe. According to the method for detecting the fluorine ions in the to-be-detected sample, the compound, or the optical isomer or the salt of the compound is used as a fluorine ion detection fluorescent probe for detection. The fluorescent probe has the advantages of good water solubility, high selectivity, high response speed, low detection limit, good stability, wide applicable pH range and good application prospect.

Controlled Reduction of Carboxamides to Alcohols or Amines by Zinc Hydrides

New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives amines. Extensive mechanistic studies by experimental and theoretical approaches imply that polymeric zinc hydride (ZnH2)∞ is responsible for alcohol formation, whereas dimeric zinc chloride hydride (H?Zn?Cl)2 is the key species for the production of amines.

FLUORIDE FLUORESCENCE PROBE

Methylene blue (MB) derivatives selectively detect F? by desilylation reaction to act as a fluorescent probe.