3419-73-6

Upstream product

• 57466-12-3 4-tert-butyl-1-methoxycyclohexene 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 77412-96-5 1-trifluoromethanesulfonyloxy-4-t-butylcyclohexene 
• 3958-47-2 triphenylindium 
• 6832-09-3 1-chloro-4-tert-butylcyclohexene 
• 960-16-7 tributylphenylstannane 
• 98-80-6 phenylboronic acid 
• 96133-27-6 4-tert-butyl-1-iodo-1-cyclohexene 
• 23525-05-5 1-bromo-4-(tert-butyl)cyclohex-1-ene 
• 591-51-5 phenyllithium 
• 21024-55-5 trans-4-tert-butyl-1-phenylcyclohexanol 
• 17807-26-0 cis-4-tert-butyl-1-phenylcyclohexanol 
• 100-59-4 phenylmagnesium chloride 
• 611235-47-3 toluene-4-sulfonic acid 4-tert-butylcyclohex-1-en-1-yl ester 

Downstream Products

• 407593-31-1 (1R,2R,4S)-1-phenyl-4-tert-butylcyclohexan-1,2-diol 
• 4127-41-7 1-phenyl-4-tert-butylcyclohexan-1,2-diol 
• 407593-29-7 1-Phenyl-cis-4-tert.-butyl-cyclohexan-cis-1,2-diol 
• 4341-22-4 1-phenyl-cis-4-t-butyl-1,2-epoxycyclohexane 
• 87830-02-2 r-1-phenyl-1-fluoro-c-2-bromo-t-4-tert-butylcyclohexane 

Relevant academic research and scientific papers

A NEW METHOD OF OLEFIN SYNTHESIS. COUPLING OF LITHIUM DIALKYLCUPRATES WITH ENOL TRIFLATES

Enol trifluoromethanesulfonates react with lithium dialkylcuprates to give the coupling products in high yields.The reaction is stereoselective and is successful with a wide variety of organocuprates , including methyl, butyl, phenyl, vinyl, and cycloprop

Visible-Light Photoredox Catalyzed Dehydrogenative Synthesis of Allylic Carboxylates from Styrenes

The visible-light photoredox/[Co(III)] cocatalyzed dehydrogenative functionalization of cyclic and acyclic styryl derivatives with carboxylic acids is documented. The methodology enables the chemo- and regioselective allylic functionalization of styryl compounds, leading to allylic carboxylates (32 examples) under stoichiometric acceptorless conditions. Intermolecular as well as intramolecular variants are documented in high yields (up to 82%). A mechanistic rationale is also proposed on the basis of a combined experimental and spectroscopic investigation.

Supramolecular Assembly of Complementary Cyanine Salt J-Aggregates

An understanding of structure-property relationships in cyanine dyes is critical for their design and application. Anionic and cationic cyanines can be organized into complementary cyanine salts, offering potential building blocks to modulate their intra/

Well-defined air-stable palladium HASPO complexes for efficient Kumada-Corriu cross-couplings of (Hetero)aryl or alkenyl tosylates

Palladium complexes of representative heteroatom-substituted secondary phosphine oxide (HASPO) preligands were synthesized and fully characterized, including X-ray crystal structure analysis. Importantly, these well-defined complexes served as highly efficient catalysts for Kumada-Corriu cross-coupling reactions of aryl, alkenyl, and even heteroaryl tosylates. Particularly, an air-stable catalyst derived from inexpensive PinP(O)H displayed a remarkably high catalytic efficacy, which resulted in cross-couplings at low catalyst loadings under exceedingly mild reaction conditions with ample scope.

METHOD FOR PRODUCING COMPOUND THROUGH COUPLING

Disclosed is a method for producing a compound (D) through coupling by subjecting an organic compound (A) having a leaving group and an organic metal compound or metal hydride compound (B) to a coupling reaction. This method is characterized in that the organic compound (A) having a leaving group and the organic metal compound or metal hydride compound (B) are reacted with each other in the presence of a catalyst composition (C) containing a transition metal compound (C-1) and a ligand (C-2) which has a coordinating group and a protic group in such a manner that the coordinating group and the protic group are next to each other. This method is useful for efficiently producing a compound through coupling.

Iodine induced transformations of alcohols under solvent-free conditions

Iodine has been shown to be an efficient catalyst for transformations of alcohols under solvent-free conditions. In the presence of 5% of iodine, tertiary alcohols underwent dehydration forming the corresponding alkenes, while in the case of 2-phenylpropane-2-ol cyclodimerisation to 1,1,3-trimethyl-3-phenylindane took place. Secondary and primary benzyl alcohols under the same conditions gave the corresponding ethers.

Palladium catalyzed Suzuki-Miyaura coupling with aryl chlorides using a bulky phenanthryl N-heterocyclic carbene ligand

A novel bis-phenanthryl N-heterocyclic carbene (NHC) based palladium acetate catalyst was effective for the coupling of various aryl and vinyl chlorides with organoboron compounds. N,N-Bis-(2,9-dicyclohexyl-10-phenanthryl)- 4,5-dihydroimidazolium chloride 8 (H2ICP·HCl) with Pd(OAc)2 and KF·18-c-6 in THF at room temperature gave Suzuki-Miyaura coupling of aryl and vinyl chorides, including unactivated and di-ortho substituted substrates in high yields. Hindered tri- and tetra-ortho substituted products were also efficiently produced. Benzyl chloride was also found to be a useful coupling partner and trimethylboroxine was used to give methylated products. The effect of ligand, base, temperature, solvent, and reaction time are reported along with various substrates including halides and triflates.

Nickel-catalyzed cross-coupling reaction of aryl fluorides and chlorides with Grignard reagents under nickel/magnesium bimetallic cooperation

Nickel-catalyzed cross-coupling of Grignard reagents with aryl (poly)fluorides or (poly)chlorides can be achieved efficiently in the presence of a new triarylphosphine ligand bearing a nearby hydroxy group. The high reactivity and the unique chemoselectivity (ArF > ArOTf ? ArSR) of the catalysis have been attributed to synergy of nickel and magnesium atoms preorganized on the ligand, as has been surmised on the basis of theoretical modeling of the reaction mechanism. Copyright

Pd/P(t-Bu)3: A mild and general catalyst for stille reactions of aryl chlorides and aryl bromides

Pd/P(t-Bu)3 serves as an unusually reactive catalyst for Stille reactions of aryl chlorides and bromides, providing solutions to a number of long-standing challenges. An unprecedented array of aryl chlorides can be cross-coupled with a range of organotin reagents, including SnBu4. Very hindered biaryls (e.g., tetra-ortho-substituted) can be synthesized, and aryl chlorides can be coupled in the presence of aryl triflates. The method is user-friendly, since a commercially available complex, Pd(P(t-Bu)3)2, is effective. Pd/P(t-Bu)3 also functions as an active catalyst for Stille reactions of aryl bromides, furnishing the first general method for room-temperature cross-couplings.

Atom-efficient metal-catalyzed cross-coupling reaction of indium organometallics with organic electrophiles

The novel metal-catalyzed cross-coupling reaction of indium organometallics with organic electrophiles is described. Triorganoindium compounds (R3In) containing alkyl, vinyl, aryl, and alkynyl groups are efficiently prepared from the correspond