6114-39-2

Basic information

• Product Name: (R)-12-Hydroxystearic acid methyl ester
• Synonyms: (R)-12-Hydroxystearic acid methyl ester;[R,(-)]-12-Hydroxystearic acid methyl ester
• CAS NO: 6114-39-2
• Molecular Formula: C₁₉H₃₈O₃
• Molecular Weight: 314.5
• Mol File: 6114-39-2.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-12-Hydroxystearic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-12-Hydroxystearic acid methyl ester(6114-39-2)
• EPA Substance Registry System: (R)-12-Hydroxystearic acid methyl ester(6114-39-2)

Safety Data

• Hazardous Substances Data: 6114-39-2(Hazardous Substances Data)

Upstream product

• 41989-07-5 methyl ricinoleate 
• 95336-35-9 6-hexyl-3-(7-methoxycarbonylheptyl)-3,6-dihydro-1,2-dioxine 
• 111-81-9 Methyl 10-undecenoate 
• 6198-58-9 methyl (Z)-vaccenate 
• 2528-61-2 Heptanoic acid chloride 
• 95080-06-1 12-Oxo-octadec-10-ynoic acid methyl ester 
• 95080-08-3 methyl 12-hydroxyoctadec-10-ynoate 
• 95189-43-8 12-hydroxyoctadec-trans-10-enoic acid 
• 95080-07-2 12-hydroxyoctadec-10-ynoic acid 
• 68396-17-8 12-oxo-octadec-9-ynoic acid 
• 2777-66-4 methyl 10-undecynoate 
• 5455-97-0 12-oxo-octadec-cis-9-enoic acid 
• 925-42-8 12-hydroxyoctadec-9-ynoic acid 
• 141-22-0 Ricinoleic acid 

Downstream Products

• 106-14-9 12-Hydroxystearic acid 
• 1852-04-6 undecanedioic acid 
• 6114-39-2 methyl 12-hydroxyoctadecanoate 
• 67123-61-9 12-(4'-nitro-4-dimethylaminoazobenzene-3'-carboxyloxy)stearic acid 
• 73640-24-1 12-(4'-nitro-4-dimethylaminostilbene-3'-carbonyloxy)stearic acid 
• 1170660-35-1 C₃₉H₅₆O₈ 

Relevant articles and documents

A General Approach to Intermolecular Olefin Hydroacylation through Light-Induced HAT Initiation: An Efficient Synthesis of Long-Chain Aliphatic Ketones and Functionalized Fatty Acids

Herein, an operationally simple, environmentally benign and effective method for intermolecular radical hydroacylation of unactivated substrates by employing photo-induced hydrogen atom transfer (HAT) initiation is described. The use of commercially available and inexpensive photoinitiators (Ph2CO and NHPI) makes the process attractive. The olefin hydroacylation protocol applies to a wide array of substrates bearing numerous functional groups and many complex structural units. The reaction proves to be scalable (up to 5 g). Different functionalized fatty acids, petrochemicals and naturally occurring alkanes can be synthesized with this protocol. A radical chain mechanism is implicated in the process.

Uncovering potential interspecies signaling factors in plant-derived mixed microbial culture

Microbes use signaling factors for intraspecies and interspecies communications. While many intraspecies signaling factors have been found and characterized, discovery of factors for interspecies communication is lagging behind. To facilitate the discovery of such factors, we explored the potential of a mixed microbial culture (MMC) derived from wheatgrass, in which heterogeneity of this microbial community might elicit signaling factors for interspecies communication. The stability of Wheatgrass MMC in terms of community structure and metabolic output was first characterized by 16S ribosomal RNA amplicon sequencing and liquid chromatography/mass spectrometry (LC/MS), respectively. In addition, detailed MS analyses led to the identification of 12-hydroxystearic acid (12-HSA) as one of the major metabolites produced by Wheatgrass MMC. Stereochemical analysis revealed that Wheatgrass MMC produces mostly the (R)-isomer, although a small amount of the (S)-isomer was also observed. Furthermore, 12-HSA was found to modulate planktonic growth and biofilm formation of various marine bacterial strains. The current study suggests that naturally derived MMCs could serve as a simple and reproducible platform to discover potential signaling factors for interspecies communication. In addition, the study indicates that hydroxylated long-chain fatty acids, such as 12-HSA, may constitute a new class of interspecies signaling factors.

Use of esters or amides of hydroxylated carboxylic acids as solubilizers

The use of esters or amides of hydroxylated carboxylic acids as solubilizers, particularly for pharmaceutical, cosmetic and food preparations, is described.