61147-34-0

Upstream product

• 74-96-4 ethyl bromide 
• 40784-95-0 2-(4-isobutylphenyl)propionitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 90708-64-8 (E/Z)-1-isobutyl-4-(prop-1-en-1-yl)benzene 

Downstream Products

• 55837-18-8 2-(4-isobutyl-phenyl)-butyric acid 
• 60682-24-8 sodium salt of 2-(4-isobutylphenyl)butyric acid 

Relevant academic research and scientific papers

Enantioselective nickel-catalyzed hydrocyanation of vinylarenes using chiral phosphine-phosphite ligands and TMS-CN as a source of HCN

Anti-headache chemistry: In the presence of a tailored modular P,P ligand the nickel-catalyzed addition of HCN, generated in situ from TMS-CN, to styrene derivatives proceeds with an unprecedented level of stereocontrol (up to 97 % ee) to give 2-aryl-acetonitriles, for example, the depicted precursor of Ibuprofen. Copyright

Phenylalkanoic compounds and therapeutic use thereof

Novel phenylalkanoic compounds of the formula I STR1 wherein R1 and R2 independently from each other represent hydrogen or alkyl with 1 to 8 carbon atoms, salts of such compounds and salts thereof, therapeutic uses of the phenylalkanoic compounds, or of the pharmacologically safe salts thereof for treating inflammatory diseases, tussive states, pain symptoms and pyretic diseases and pharmaceutical composition containing the phenylalkanoic compounds or the pharmacologically safe salts together with a carrier and an optional adjuvant or additive.