61198-84-3Relevant academic research and scientific papers
Syntheses of Selectively Alkylated Enol Ethers in the L-ribo Series
Koepper, Sabine,Lundt, Inge,Pedersen, Christian,Thiem, Joachim
, p. 531 - 536 (2007/10/02)
The reduction of enulose 1a predominantly leads to L-digitoxal (3a), although this method presents a sluggish reaction with moderate yields.In contrast, the preparation from L-digitoxose (4a) in a three-step one-pot procedure represents an advantageous approach.Regioselective 3- or 4-O-alkylations are achieved by phase-transfer catalysis method or via stannylidene intermediates to give monosaccharide precursors of the L-ribo series valuable for further interglycosidic linking.
