612083-62-2

Basic information

• Product Name: Pyrrolo[1,2-b]pyridazine-3-carbonitrile, 6-(1-hydroxy-1-methylethyl)-5-methyl-4-[(4-phenoxyphenyl)amino]-
• CAS NO: 612083-62-2
• Molecular Formula: C24H22N4O2
• Molecular Weight: 398.464
• Mol File: 612083-62-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyrrolo[1,2-b]pyridazine-3-carbonitrile, 6-(1-hydroxy-1-methylethyl)-5-methyl-4-[(4-phenoxyphenyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[1,2-b]pyridazine-3-carbonitrile, 6-(1-hydroxy-1-methylethyl)-5-methyl-4-[(4-phenoxyphenyl)amino]-(612083-62-2)
• EPA Substance Registry System: Pyrrolo[1,2-b]pyridazine-3-carbonitrile, 6-(1-hydroxy-1-methylethyl)-5-methyl-4-[(4-phenoxyphenyl)amino]-(612083-62-2)

Safety Data

• Hazardous Substances Data: 612083-62-2(Hazardous Substances Data)

Upstream product

• 612083-24-6 3-Cyano-5-methyl-4-[(4-phenoxyphenyl)amino]pyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester 
• 427878-69-1 1-amino-3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester 
• 5448-16-8 3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester 
• 612085-98-0 3-Cyano-1,4-dihydro-5-methyl-4-oxopyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester 
• 612085-99-1 4-Chloro-3-cyano-5-methylpyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 612083-63-3 6-Hydroxy-5-methyl-4-(4-phenoxy-phenylamino)-pyrrolo[1,2-b]pyridazine-3-carbonitrile 

Relevant articles and documents

Pyrrolopyridazine MEK inhibitors

The synthesis and SAR of a series of pyrrolopyridazine MEK inhibitors are reported. Optimal activity was achieved by incorporation of a 4-phenoxyaniline substituent at C4 and an acylated amine at C6.