61229-06-9

Usage

Uses

Used in Food Additives Industry:
(5E)-7-methyloct-5-enoic acid is used as a flavoring agent for enhancing the taste and aroma of food products, capitalizing on its natural presence in certain plants and its ability to contribute to the overall sensory experience.
Used in Pharmaceutical Industry:
(5E)-7-methyloct-5-enoic acid is used as an active pharmaceutical ingredient for its potential health benefits and therapeutic applications, leveraging its unique structure and characteristics to address specific medical needs.
Used in Fragrance Industry:
(5E)-7-methyloct-5-enoic acid is used as a component in creating various fragrances, taking advantage of its natural occurrence in plants and its ability to contribute to the development of distinct and appealing scents.
Used in Industrial Applications:
(5E)-7-methyloct-5-enoic acid is used in various industrial processes due to its chemical properties, which make it a valuable component in the development and production of different products.

Upstream product

• 143211-17-0 (E)-1-hydroxy-7-methyloct-5-ene 
• 42186-61-8 5-(Triphenyl-λ⁵-phosphanylidene)-pentanoic acid anion 
• 78-84-2 isobutyraldehyde 
• 5454-83-1 5-bromovaleric acid methyl ester 
• 6026-86-4 methyl 4-formylbutanoate 
• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 14273-92-8 methyl 5-hydroxypentanoate 
• 143211-14-7 (Z)-1-hydroxy-7-methyloct-5-ene 
• 694-54-2 tetrahydro-2H-2-pyranol 
• 179617-47-1 trans-6-methyl-hept-4-enoic acid ethyl ester 
• 179617-41-5 Methanesulfonic acid (E)-6-methyl-hept-4-enyl ester 
• 59721-82-3 (E)-1-hydroxy-6-methylhept-4-ene 
• 142331-60-0 (E)-7-methyl-5-octenenitrile 
• 112375-53-8 (E)-methyl 7-methyloct-5-enoate 

Downstream Products

• 112375-57-2 (E)-7-Methyloct-5-enoic acid chloride 
• 693-19-6 isononoic acid 
• 28789-35-7 Nordihydrocapsaicin 
• 61229-08-1 norcapsaicin 

Relevant academic research and scientific papers

Total synthesis of (+)-epopromycin B and its analogues - Studies on the inhibition of cellulose biosynthesis

The described inhibition of the cellulose biosynthesis by epopromycin B prompted us to establish a short and efficient synthesis of the natural product, suitable for accessing a broad range of unnatural analogues in a multiparallel fashion. During the course of our synthesis the absolute configuration of (+)-epopromycin B could be determined.

A general and stereoselective synthesis of the capsaicinoids via the orthoester Claisen rearrangement

Capsaicin, a main pungent principle of hot pepper, and its 15 analogs have been efficiently synthesized. The key step of this synthetic scheme is the orthoester Claisen rearrangement, which transformed allylic alcohols 2A-C to (E)-alkenoates 3A-C (E/Z > 100) in a highly stereoselective manner. The subsequent carbon chain elongations on 3 based on the cyanation or the malonic acid ester synthesis afforded (E)-alkenoic acids 8, which were converted to the corresponding acid chloride and then coupled with vanillylamine to give capsaicinoids. HPLC and CE (capillary electrophoresis) analyses of these capsaicinoids were also carried out.

An Alternate Synthesis of the Capsaicinoids

Five capsaicinoids, the pungent ingredients of hot peppers, have been efficiently synthesized by a method involving the Wittig reaction between isobutyl triphenylphosphorane and the appropriate lactols (3), followed by the nitrous acid-induced isomerization of the resultant (Z)-olefins (4) to (E)-olefins (5).

The Capsaicinoids: Their Separation, Synthesis, and Mutagenicity

Capsaicin (1b), the pungent ingredient in many varietes of Capsicums has recently been implicated as a possible carcinogen.When obtained from natural sources 1b is always accompanied by a number of related homologues.We have isolated seven of these homologues, characterized them, and synthesized them by a general and unique route developed in our laboratories.Also reported are mutagenicity data for 1b and an extract of red pepper as measured by the Ames assay and the V-79 mammalian cell assay.

TRANS STEREOSELECTIVITY IN THE REACTION OF (4-CARBOXYBUTYLIDENE)TRIPHENYLPHOSPHORANE WITH AROMATIC ALDEHYDES

Aromatic aldehydes react with 1 to give predominantly trans 6-aryl-5-hexenoic acids, under special conditions.A systematic study of the reaction of 1 with aldehydes, in a preliminary attempt to define the cause and scope of the trans stereoselectivity, is reported.