693-19-6Relevant articles and documents
Method for preparing alkane carboxylic acid by increasing alkane carbon chains
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, (2021/06/09)
The invention discloses a method for preparing alkane carboxylic acid by increasing alkane carbon chains. The method comprises the following steps: (1) carrying out Stork enamine alkylation on cyclopentanone or cyclohexanone and a secondary amine compound to generate a corresponding 1-position secondary amine substituted cyclopentene or cyclohexene crude product, namely Stork enamine; (2) carrying out electrophilic reagent reaction on the Stork enamine and acyl halide to form a 2-acyl cyclic ketone compound; and (3) carrying out ring opening on the 2-acyl cyclic ketone compound under the action of alkali to generate a carbonyl carboxylic acid compound, and carrying out a Wolff-Huang Minglong reduction reaction on the carbonyl carboxylic acid compound to obtain the corresponding alkane carboxylic acid. According to the method disclosed by the invention, cyclopentanone or cyclohexanone can be flexibly selected to meet the requirement of increasing different carbon numbers according to the required carbon number and different sources of target carburant alkane carboxylic acid or corresponding acyl halide. The method has the advantages of simple reaction process and no complex operation difficulty, and is suitable for industrial mass production.
Method for catalytically oxidizing primary alcohol into corresponding carboxylic acid and simultaneously co-producing corresponding alpha olefin
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Paragraph 0032-0033; 0040-0041, (2020/12/30)
The invention relates to a method for catalytically oxidizing primary alcohol into corresponding carboxylic acid and simultaneously co-producing corresponding alpha olefin. The method comprises the following steps: mixing primary alcohol shown as a substrate (I), a catalyst cobalt salt, a nitrogen-containing ligand and a solvent, refluxing and stirring for 4-48 hours in an oxygen or air atmospherewith a certain pressure, and distilling and separating the reacted liquid to obtain carboxylic acid shown as (II) and alpha olefin in a certain proportion. The cobalt salt catalyst used in the methodis cheap and easy to obtain, the used nitrogen-containing ligand is a commercial nitrogen-containing compound, the used oxidant is oxygen or air, the reaction condition is mild, and various primary alcohols can be converted into corresponding carboxylic acids and alpha olefins at a high conversion rate under the condition of low cost.
Method for preparing carboxylic acid by green catalytic oxidation of aliphatic primary alcohol
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Paragraph 0037-0042; 0071-0082, (2020/12/30)
The invention relates to a method for preparing carboxylic acid by green catalytic oxidation of aliphatic primary alcohol. The method comprises the following steps of: adding aliphatic primary alcoholinto a reaction solvent, adding an N-hydroxyphthalimide-copper oxide catalyst, introducing oxygen during reaction, and carrying out reaction at 50-80DEG C under normal pressure for 6-24h to obtain carboxylic acid with high yield. Compared with the prior art, the method has the advantages that the oxidizing agent is green and environment-friendly, the catalyst is cheap and easy to prepare, easy toseparate from the product, convenient to recycle, the reaction conditions are mild and the like, therefore the method is a green oxidation method of aliphatic primary alcohol.
