6123-67-7

Upstream product

• 205113-77-5 5-methyl-1-phenyl-1H-pyrazole-4-carbonyl chloride 
• 71-43-2 benzene 
• 100-63-0 phenylhydrazine 
• 59-88-1 phenylhydrazine hydrochloride 
• 67-68-5 dimethyl sulfoxide 
• 56570-63-9 ((E)-3-(dimethylamino)-1-phenylbut-2-en-1-one) 
• 59068-34-7 5-acetyl-2,4-diphenylpyrimidine 
• 59068-33-6 2-ethoxymethylene-1-phenyl-1,3-butanedione 

Relevant academic research and scientific papers

DMSO as a C1 Source for [2 + 2 + 1] Pyrazole Ring Construction via Metal-Free Annulation with Enaminones and Hydrazines

A cascade reaction between enaminones, hydrazines, and dimethyl sulfoxide (DMSO) for the synthesis of 1,4-disubstituted pyrazoles catalyzed by molecular iodine in the presence of Selectfluor has been realized. DMSO plays a dual role as the C1 source and the reaction medium. In addition, the synthesis of 1,3,4-trisubstituted pyrazoles using aldehydes as alternative C1 building blocks has also been achieved.

Reactions of 2-ethoxymethylene-1,3-diketones with hydrazine and phenylhydrazine

Reactions of 1-aryl-2-etoxymethylene-1,3-butanediones (Ar = Ph, MeO, Cl) with hydrazine and phenylhydrazine in CHCl3 and CH3OH were studied by 1H NMR spectroscopy in the temperature range from -30 to 50°C. The products are

Synthesis of 1H-Thieno[3,4-c]pyrazoles, Thieno[3,4-b]furans, Selenolo[3,4-b]furans and Pyrrolo[3,4-d]thiazoles

Starting from the readily available aryl 2-methyl-5-phenyl-3-furyl ketones, 5-methyl-1H-1-phenylpyra- zole-4-yl ketones and 4-methyl-2-phenyl-5-thiazolylcarboxaldehyde, a series of 2-phenyl-4-arylthieno[3,4-b]-furan, 2-phenyl-4-(p-methoxyphenyl)selenolo[3,4-b]furan, 4-aryl-1H-1-phenylthieno[3,4-c]pyrazole and 5-benzyl-2-phenylpyrrolo[3,4-d]thiazole were prepared in high yield.