61236-93-9Relevant academic research and scientific papers
Anti-coagulation pentasaccharide and preparing method and medical application thereof
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Paragraph 0105; 0109, (2019/01/23)
The invention relates to an anti-coagulation medicine, in particular to a synthesized pentasaccharide compound, salt thereof, and a preparing method and medical application of the pentasaccharide compound. The pentasaccharide compound or acid or salt thereof in the ion form shown in the formula III (the formula can be seen in the description) is synthesized and has stronger anti-coagulation factorXa activity and a longer elimination half life compared with sodium sulfonate. The pentasaccharide compound can be used for preparing medicines for preventing and treating blood coagulation disorderrelated diseases such as deep venous thrombosis, thrombophlebitis, artery blockage caused by thrombosis or embolism and postoperative vein thrombosis or embolism.
Cyclodextrin - a Carrieir of Synthon? Synthesis of per-O-Methyl-β-cyclodextrin-GM3
Hique, W.,Diakur, J.
, p. 17 - 30 (2007/10/03)
Cyclodextrins are currently under imnvestigation for their utility as drug delivery agents. One property of the parent cyclic oligosaccharides which requires further modification for advanced drug delivery applications is that of site-directing capability
Stereoselective Synthesis of 1- and 2-O-α-D-Cellotriosyl-3-deoxy-2(R)- and 2(S)-glycerols Related to Rhynchosporoside
Sugawara, Fumio,Nakayama, Haruhiko,Stroebel, Gary A.,Ogawa, Tomoya
, p. 2261 - 2272 (2007/10/02)
The stereoselective synthesis of 1- and 2-O-α-D-cellotriosyl-3-deoxy-2(R)- and 2(S)-glycerols, which determined the structure of rhynchosporoside produced by Rhynchosporium secalis, and their phytotoxicity toward the host plant (Hordeum vulgare) are described in detail.
