24679-79-6

Upstream product

• 61893-74-1 allyl 2,3,6-tri-O-benzyl-α-D-galactopyranoside 
• 19488-48-3 methyl 2,3,6-tri-O-benzyl-α-D-galactopyranoside 
• 100-39-0 benzyl bromide 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 
• 7177-79-9 methyl 2,3-O-dibenzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 19488-48-3 methyl O-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 129318-82-7 2,3,6-Tri-O-benzyl-β-cyclomaltoheptaose 
• 99388-26-8 benzyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 7177-79-9 methyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 3162-96-7 methyl 4,6-O-benzylidene-α-D-glucopyranoside 
• 19488-48-3 methyl 2,3,6-tri-O-benzyl-D-glucopyranoside 
• 100759-11-3 allyl 2,3-di-O-benzyl-4,6-di-O-benzylidene-α-D-galactopyranoside 
• 100759-10-2 allyl 4,6-di-O-benzylidene-α-D-galactopyranoside 
• 2595-07-5 allyl D-galactopyranoside 

Downstream Products

• 61236-93-9 1,4-di-O-acetyl-2,3,6-tri-O-benzyl-D-glucopyranoside 
• 24679-80-9 2,3,6-Tri-O-benzyl-α-D-glucopyranosyl chloride 
• 129318-83-8 2-Benzyloxy-3,6-di-O-benzyl-D-glucal 
• 52562-57-9 1,4-anhydro-2,3,6-tri-O-benzyl-α-D-glucopyranose 
• 357674-74-9 2-(p-nitrophenyl)ethyl O-(2,3,4,6-terta-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 357674-75-0 2-(p-nitrophenyl)ethyl (β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 357674-72-7 2-(p-nitrophenyl)ethyl 4-O-acetyl-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 357674-73-8 2-(p-nitrophenyl)ethyl 2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 61236-94-0 4-O-acetyl-2,3,6-tri-O-benzyl-α-D-glucopyranosyl chloride 
• 84218-71-3 4-O-acetyl-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 736969-67-8 4-O-acetyl-2,3,6-tri-O-benzyl-α,β-D-glucopyranosyl trichloroimidate 
• 912650-58-9 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-manno-hept-2-ulosyl-(2->4)-2,3,6-tri-O-benzyl-D-galactono-1,5-lactone 
• 912650-55-6 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulosyl-(2->4)-2,3,6-tri-O-benzyl-D-galactono-1,5-lactone 
• 912650-52-3 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-gluco-hept-2-ulosyl-(2->4)-2,3,6-tri-O-benzyl-D-galactono-1,5-lactone 

Relevant academic research and scientific papers

Anti-coagulation pentasaccharide and preparing method and medical application thereof

The invention relates to a synthesized pentasaccharide compound, salt thereof, and application of the pentasaccharide compound in preparing medicines for preventing and/or treating blood coagulation disorder related diseases.

Anti-coagulation pentasaccharide and preparing method and medical application thereof

The invention relates to an anti-coagulation medicine, in particular to a synthesized pentasaccharide compound, salt thereof, and a preparing method and medical application of the pentasaccharide compound. The pentasaccharide compound or acid or salt thereof in the ion form shown in the formula III (the formula can be seen in the description) is synthesized and has stronger anti-coagulation factorXa activity and a longer elimination half life compared with sodium sulfonate. The pentasaccharide compound can be used for preparing medicines for preventing and treating blood coagulation disorderrelated diseases such as deep venous thrombosis, thrombophlebitis, artery blockage caused by thrombosis or embolism and postoperative vein thrombosis or embolism.

Anti-coagulation pentasaccharide compound and preparing method and medical application thereof

The invention relates to an anti-coagulation medicine, in particular to a synthesized pentasaccharide compound, salt thereof, and a preparing method and medical application of the pentasaccharide compound. The pentasaccharide compound or acid or salt thereof in the ion form shown in the formula II (the formula can be seen in the description) is synthesized and has stronger anti-coagulation factorXa activity and a longer elimination half life compared with sodium sulfonate. The pentasaccharide compound can be used for preparing medicines for preventing and treating blood coagulation disorder related diseases such as deep venous thrombosis, thrombophlebitis, artery blockage caused by thrombosis or embolism and postoperative vein thrombosis or embolism.

Four Different Regioisomeric Polycarbonates Derived from One Natural Product, d -Glucose

Strategies for the preparation of polycarbonates, derived from the natural product d-glucose, which have the potential to degrade back into their bioresorbable starting material and CO2, were developed. By employing established carbohydrate pro

On the synthesis of vinyl and phenyl C-furanosides by stereospecific debenzylative cycloetherification

Open-chain benzyl-ether-protected polyols in which one of the alcohols is either allylic or benzylic are synthesised by addition of organometallic vinyl or phenyl reagents to benzyl-ether-protected carbohydrate hemiacetals. The diastereoselectivity of add

Synthesis of 1-deoxyhept-2-ulosyl-glycono-1,5-lactone utilizing α-selective O-glycosidation of 2,6-anhydro-1-deoxy-d-hept-1-enitols

A series of 1-deoxy-heptulo-2-pyranosyl-glycono-1,5-lactones were synthesized utilizing completely α-selective O-glycosidation of heptenitols. Anomeric configuration of the products was confirmed by 3JC,H coupling measurement and X-ray crystal structural analysis. The benzyl-protected ketosyl saccharides were partly unstable, and glycosidic linkage was prone to cleave under the usual debenzylation conditions. To prevent this, we surveyed various additives for the Pd-catalyzed hydrogenation reaction and found that basic alumina was the most effective.

Hydrothermolysis of the fully benzylated α-cyclodextrin

The treatment of the fully benzylated α-cyclodextrin with the hot compressed mixed solvent of dioxane/water (v/v=1/1) at 270 °C and 150 kg/cm2 for 40 min afforded 2,3,6-tri-O-benzyl-D-glucopyranose in good yield. The hydrothermolysis of the ful

α-glucosidase inhibitors

This invention relates to novel N-glycosyl derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol, to the chemical processes for their preparation, to their α-glucosidase inhibiting properties, and to their end-use application in the treatment of diabetes, obe

Synthesis of 1,4-anhydro-2,3,6-tri-O-benzyl-α-D-glucopyranose by cis-ring-closure of a glycosyl chloride

A synthetic approach to 1,4-anhydro-2,3,6-tri-O-benzyl-α-D-glucopyranose by cis-ring closure of a glycosyl chloride has been studied to furnish a starting sugar for the synthesis of a linear (1->4)-linked polysaccharide.Cyclomaltoheptaose was benzylated and the product hydrolyzed to afford 2,3,6-tri-O-benzyl-α-D-glucopyranose, which was converted by HCl-Et2O into the corresponding glycosyl chloride.Treatment of the latter with NaH in Me2SO gave mainly 2-benzyloxy-3,6-di-O-benzyl-D-glucal, with 1,4-anhydro-2,3,6-tri-O-benzyl-α-D-glucopyranose as a byproduct.However, the 1,4-anhydro sugar could be prepared in good yield by cis ring-closure of 2,3,6-tri-O-benzyl-α-D-glucopyranosyl chloride in a mixture of tetrahydrofuran and sodium hydride.

Novel alpha-glucosidase inhibitors

This invention relates to novel N-derivatives, of 1,4-di--deoxy-1,4-imino-L-arabinitol (I), to the processes for their preparation and to their end-use applications, particularly as to their use in the treatment of diabetes. wherein n is zero, one or two,