61289-10-9Relevant academic research and scientific papers
Automated modular synthesis of Aptamer-drug conjugates for targeted drug delivery
Wang, Ruowen,Zhu, Guizhi,Mei, Lei,Xie, Yan,Ma, Haibin,Ye, Mao,Qing, Feng-Ling,Tan, Weihong
supporting information, p. 2731 - 2734 (2014/03/21)
Aptamer-drug conjugates (ApDCs) are promising targeted drug delivery systems for reducing toxicity while increasing the efficacy of chemotherapy. However, current ApDC technologies suffer from problems caused by the complicated preparation and low control
Synthesis of 1- and 3-Arylcarbonyl Derivatives of 5-Fluorouracil
Perrin, John H.,Underberg, William J.,Sloan, Kenneth B.
, p. 397 - 402 (2007/10/03)
4'-Substituted 1-arylcarbonyl-5-fluorouracil derivatives were synthesized from the reaction of the potassium salt of 5-fluorouracil with one equivalent of aryl acid chloride in acetonitrile. 4'-Substituted 3-arylcarbonyl-5-fluorouracil derivatives were sy
Studies on the Synthesis of Chemotherapeutics. 10. Synthesis and Antitumor Activity of N-Acyl- and N-(Alkoxycarbonyl)-5-fluorouracil Derivatives
Kametani, Tetsuji,Kigasawa, Kazuo,Hiiragi, Mineharu,Wakisaka, Kikuo,Haga, Seiji,et al.
, p. 1324 - 1329 (2007/10/02)
A number of N-acyl and N-(alkoxycarbonyl)-5-fluorouracil derivatives possessing for example, benzoyl, o-toluyl, acetyl, propionyl, heptanoyl, etoxycarbonyl, phenoxycarbonyl, and benzyloxycarbonyl groups as N1 and/or N3 substituents w
5-Fluorouracil derivatives
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, (2008/06/13)
A compound represented by the formulae: STR1 wherein R1 and R2 are as defined hereinafter, useful as an anti-cancer or anti-tumor agent.
