613233-75-3

Upstream product

• 81227-89-6 2-[4-(methylmercapto)phenyl]-1-ethanol 
• 16188-55-9 2-(4-(methylthio)phenyl)acetic acid 

Downstream Products

• 613233-73-1 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9α-(3'-(p-methylthiophenyl)propyl)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 613233-57-1 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9β-(3'-(p-methylthiophenyl)propyl)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 919360-57-9 4-[2-ethoxycarbonyl-4-(4-methylsulfanylphenyl)butyryl]piperidine-1-carboxylic acid tert-butyl ester 
• 613233-58-2 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9β-(3'-(p-methanesulfonylphenyl)propyl)-12H-pyrano-[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 320407-92-9 4-(bromomethyl)-2-chloro-1-methoxybenzene 
• 55153-95-2 4-methanesulfinylphenethyl bromide 

Relevant academic research and scientific papers

CYCLIC TERTIARY AMINE COMPOUND

The present invention provides a cyclic tertiary amine compound which is capable of inhibiting the production of inflammatory cytokines. It is either a compound having a structure represented by the following general formula (I): (wherein A represents an optionally substituted trivalent group derived from pyrimidine, pyrrole, or the like; R1 represents an aryl or a heteroaryl group which may optionally be substituted; R2 represents a heteroaryl group which may optionally be substituted; and R3 represents a cyclic tertiary amino group) or a pharmacologically acceptable salt of the compound.

Structure-activity relationships of the antimalarial agent artemisinin. 8. Design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria

Artemisinin (1) and its analogues have been well studied for their antimalarial activity. Here we present the antimalarial activity of some novel C-9-modified artemisinin analogues synthesized using artemisitene as the key intermediate. Further, antileish

ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS

Described herein is the synthesis, bioassay results and utility of new C-9 and C-10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.