613233-58-2

Upstream product

• 81227-89-6 2-[4-(methylmercapto)phenyl]-1-ethanol 
• 63968-64-9 C₁₂H₁₃O₂(CH₃)3(O)(OO) 
• 613233-75-3 p-(methylthio)phenethyl bromide 
• 613233-73-1 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9α-(3'-(p-methylthiophenyl)propyl)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 467223-78-5 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9β-(phenylthio)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 101020-89-7 dehydroqinghaosu 
• 16188-55-9 2-(4-(methylthio)phenyl)acetic acid 
• 613233-57-1 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9β-(3'-(p-methylthiophenyl)propyl)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 

Relevant academic research and scientific papers

Structure-activity relationships of the antimalarial agent artemisinin. 8. Design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria

Artemisinin (1) and its analogues have been well studied for their antimalarial activity. Here we present the antimalarial activity of some novel C-9-modified artemisinin analogues synthesized using artemisitene as the key intermediate. Further, antileish

ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS

Described herein is the synthesis, bioassay results and utility of new C-9 and C-10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.