613663-53-9Relevant academic research and scientific papers
SAR study of 2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepines as progesterone receptor agonists
Dols, Paul P.M.A.,Folmer, Brigitte J.B.,Hamersma, Hans,Kuil, Cor W.,Lucas, Hans,Ollero, Lourdes,Rewinkel, Jos B.M.,Hermkens, Pedro H.H.
, p. 1461 - 1467 (2008)
We have developed a new class of progesterone receptor agonists having a tetracyclic dibenzo-oxazepine structure 1. In this paper, the synthesis and structure-activity relationships of this new class are described. This work led to the identification of p
NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS
-
Page/Page column 17; 62, (2010/02/07)
The present invention provides compounds according to general Formula (I), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt of a prodrug thereof. More particularly, the present invention provides high affinity non-steroidal compounds which are agonists, partial agonists or antagonists of the progesterone receptor.
