613667-09-7Relevant academic research and scientific papers
Cu-Catalyzed Three-Component Coupling of Aryne, Alkyne, and Benzenesulfonothioate: Modular Synthesis of o-Alkynyl Arylsulfides
Peng, Xianglong,Ma, Chen,Tung, Chen-Ho,Xu, Zhenghu
, p. 4154 - 4157 (2016)
A copper-catalyzed three-component coupling reaction of in situ formed arynes, terminal alkynes, and benzenesulfonothioates is described. This reaction provides an efficient modular synthesis of o-alkynyl arylsulfides from easily available starting materials. This process involves one C-S bond and one C-C bond formation in one pot.
Studies into diastereoselective D?tz benzannulations for the synthesis of axially chiral biaryls
Anderson, James C.,Cran, John W.,King, N. Paul
, p. 7771 - 7774 (2007/10/03)
A series of racemic chiral ortho substituents on 1-phenylhex-1-yne have been found to control the atroposelective formation of a biaryl from D?tz benzannulation with pentacarbonyl(methoxyphenylmethylene)chromium(0). The results show there is a subtle balance between the chiral ortho substituent controlling atroposelectivity with a dr 3-5:1 and allowing benzannulation to proceed in yields of 44-67%.
