613667-10-0Relevant academic research and scientific papers
Studies into diastereoselective D?tz benzannulations for the synthesis of axially chiral biaryls
Anderson, James C.,Cran, John W.,King, N. Paul
, p. 7771 - 7774 (2007/10/03)
A series of racemic chiral ortho substituents on 1-phenylhex-1-yne have been found to control the atroposelective formation of a biaryl from D?tz benzannulation with pentacarbonyl(methoxyphenylmethylene)chromium(0). The results show there is a subtle balance between the chiral ortho substituent controlling atroposelectivity with a dr 3-5:1 and allowing benzannulation to proceed in yields of 44-67%.
