61367-07-5

Basic information

• Product Name: methyl 4-aminocyclohexane-1-carboxylate
• Synonyms: methyl 4-aminocyclohexane-1-carboxylate;Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride;Nsc145378;Methyl 4-aminocyclohexanecarboxylate hydrochloride;trans-4-AMino-cyclohexanecarboxylic acid Methyl ester hydrochloride;Trans-Methyl 4-aMinocyclohexanecarboxylate HCl;trans-4-AMino-cyclohexanecarboxylic acid Methyl ester;trans-Methyl 4-aMinocyclohexanecarboxylate hydrochloride
• CAS NO: 61367-07-5
• Molecular Formula: C₈H₁₅NO₂*ClH
• Molecular Weight: 193.67
• Mol File: 61367-07-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 255.4°C at 760 mmHg
• Flash Point: 108.3°C
• Appearance: /
• Vapor Pressure: 0.0129mmHg at 25°C
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility: Soluble in water.
• CAS DataBase Reference: methyl 4-aminocyclohexane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-aminocyclohexane-1-carboxylate(61367-07-5)
• EPA Substance Registry System: methyl 4-aminocyclohexane-1-carboxylate(61367-07-5)

Safety Data

• Hazardous Substances Data: 61367-07-5(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

Uses

Methyl trans-4-aminocyclohexanecarboxylate hydrochloride is generally used as a intermediate in pharmaceutical and chemical research.

InChI:InChI:1S/C8H15NO2.ClH/c1-11-8(10)6-2-4-7(9)5-3-6;/h6-7H,2-5,9H2,1H3;1H

Upstream product

• 67-56-1 methanol 
• 1776-53-0 trans-4-aminocyclohexanecarboxylic acid 
• 146307-51-9 methyl (1R,4R)-4-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate 

Downstream Products

• 727736-49-4 methyl trans-4-[(3-hydroxypropanoyl)amino]cyclohexanecarboxylate 
• 412293-70-0 methyl trans-4-(morpholin-4-ylcarbonyl)cyclohexane carboxylate 
• 727737-09-9 methyl trans-4-(pyrrolidin-1-ylcarbonyl)cyclohexane carboxylate 
• 727736-96-1 methyl trans-4-({2-[(t-butoxycarbonyl)amino]ethyl}amino)-cyclohexanecarboxylate 
• 609805-47-2 methyl trans-4-(morpholin-4-yl)cyclohexanecarboxylate 
• 727737-07-7 methyl (1r,4r)-4-(dimethylcarbamoyl)cyclohexane-1-carboxylate 
• 609805-43-8 methyl trans-4-dimethylaminocyclohexanecarboxylate 
• 609805-64-3 methyl trans-4-({[2-(2-benzyloxy)ethoxy]acetyl}amino)cyclohexanecarboxylate 
• 727736-51-8 methyl trans-4-{[(3-chloropropyl)sulfonyl]amino}cyclohexanecarboxylate 
• 150594-70-0 6-(4-Cyanophenyl)-4-[[trans-4-(methoxycarbonyl)-cyclohexyl]-aminocarbonyl]-2-[(morpholinocarbonyl)-methyl]-(2H)-pyridazin-3-one 
• 733784-92-4 methyl trans-4-(1-piperidyl)cyclohexanecarboxylate 
• 727736-47-2 methyl trans-4-(glycoloylamino)cyclohexanecarboxylate 
• 1207529-77-8 (1r,4r)-methyl 4-(5-chloro-2-methylnicotinamido)cyclohexanecarboxylate 
• 126385-78-2 methyl (1r,4r)-4-benzamidocyclohexane-1-carboxylate 

Relevant articles and documents

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS

Compounds of Formula (I) and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.

FUSED FURAN COMPOUND

The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and , R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.